Lung
Small Cell Lung Cancer:
IRB #H-29718/RTOG #R0937: Randomized Phase II Study Comparing Prophylactic Cranial Irradiation alone to Prophylactic Cranial Irradiation and Consolidative Extra-Cranial Irradiation for Extensive Disease Small Cell Lung Cancer (ED-SCLC)
NSCLC – Adjuvant:
CIRB #H-31593/SWOG #E1505: Phase III Randomized, Adjuvant Chemotherapy with or without Avastin in Completely Resected Stage IB (greater than or equal to 4 cm)-IIIA Non-Small Cell Lung Cancer
NSCLC – Locally Advanced:
IRB #H-26701: Feasibility and Outcome of CyberKnife Precision Hypofractionated Radiosurgery for Curative Management of Non-Small Cell Lung Cancer
CIRB #H-31165/ACOSOG #Z4099: A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) versus Stereotactic Body Radiation Therapy in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)
NSCLC – Locally Advanced/Metastatic:
CIRB #H-30283/CTSU #C30801: A Randomized Phase III Double Blind Trial Evaluating Selective COX-2 Inhibition in COX-2 Expressing Advanced Non-Small Cell Lung Cancer
IRB #H-31391/RTOG #R0839: Randomized Phase II Study of Pre-Operative Chemoradiotherapy +/- Panitumumab (IN #110152) Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer
IRB #H-pend/SWOG #S1206:
A Dose Finding Study Followed by Phase II Randomized, Placebo-Controlled Study of Veliparib (ABT-888) Added Chemoradiotherapy with Carboplatin and Paclitaxel for Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC), (NCI Study Number 8811) (pending IRB approval)
Symptom Management:
IRB #H-31584/RTOG #R1012:
Phase II Randomized Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy Induced Esophagitis-Related Pain During the Treatment of Lung Cancer (RT requirements not met
