Alexander Walley, MD, MSc

CARE Unit Faculty


Assistant Professor of Medicine, Boston University School of Medicine

Medical Director, Opioid Treatment Program, Boston Public Health Commission

Medical Director, Massachusetts Department of Public Health, Opioid Overdose Prevention Program

Co-Program Director, Boston University Addiction Medicine Residency Program

Program Director, Fellow Immersion Training Program

Crosstown Center, 801 Massachusetts Ave., 2nd Floor, Boston, MA 02118


Dr. Walley is an Assistant Professor of Medicine at Boston University School of Medicine (BUSM) and a general internist who provides primary care for HIV-infected patients at BMC and is the medical director of the Boston Public Health Commission’s Opioid Treatment Program.  His research interests include the medical complications of drug use, specifically HIV and overdose, the treatment of addictions with behavioral and pharmacologic interventions, and risk behaviors among HIV-infected people and people with HIV risk behaviors.  He is an investigator on studies of the integration of addiction treatment into primary medical care for people with HIV infection or high risk for HIV, a behavioral intervention to reduce alcohol use and risky sexual behavior among HIV-infected alcohol-using Russians, and the implementation of an opioid overdose prevention program.  He routinely mentors summer research students and leads the Boston Medical Center Internal Medicine Primary Care Resident Addiction Medicine Block Rotation.

Boston University faculty appointment: 2007

Areas of Specialization

  • Medical complications of addiction, including HIV infection and overdose

Education and Training

General Internal Medicine, Boston University School of Medicine/ Boston Medical Center Boston, MA  2005-07

Chief resident (Internal Medicine), San Francisco General Hospital, University of California, San Francisco CA
Resident (Internal Medicine), San Francisco General Primary Care Program, University of California, San Francisco, CA  2000-2003

MD, John Hopkins University School of Medicine Baltimore, MD 
MSc (Epidemiology) Boston University School of Public Health, Boston, MA
AB (History and Literature) Harvard University, Cambridge, MA

Honors and Awards

  • Evans Junior Faculty Merit Award, Boston University School of Medicine, Department of Medicine,  2011 
  • Junior Faculty Mentoring Award, Boston University School of Medicine, Department of Medicine,  2011 
  • Clinician Investigator Award, New England Region Society of General Internal Medicine,  2010

Key Publications

Walley AY, Paasche-Orlow M, Lee EC, Forsythe S, Chetty VK, Mitchell S, Jack BW. Acute care hospital utilization among medical inpatients discharged with a substance use disorder diagnosis. Journal of Addiction Medicine. 2012 (6):50-6.

Walley AY, Farrar D, Cheng DM, Alford DP, Samet JH. Is methadone maintenance treatment and indication missing from the medical record? A patient safety issue. Journal of General Internal Medicine. 2009 (24): 1007-11.

Doe-Simkins M*, Walley AY*, Epstein A, Moyer P. Saved by the nose: Bystander-administered intranasal naloxone for opioid overdose. American Journal of Public Health.2009 (99): 788-91. *Co-first authors

Walley AY, Alperen JK, Cheng, DM, Botticelli M, Castro-Donlan C, Samet JH, Alford, DP. Office-based management of opioid dependence with buprenorphine: Clinical practices and barriers. Journal of General Internal Medicine. 2008(23): 1393-8.

Walley AY, Cheng DM, Libman H, Nunes DP, Saitz R, Samet JH.  Recent drug use, homelessness and increased short-term mortality in HIV-infected persons with alcohol problems.  AIDS 2008 (22): 415-20.

Publications and NIH Grant Support