Modification of Cardiovascular Proteins by Metabolic Disease
A wide variety of academic faculty members combined to create the Cardiovascular Proteomics Center under the direction of Dr. Catherine E. Costello. CPC is a research institute studying oxidative stress using proteomics technologies. The faculty, true to the multi-disciplinary nature of cross-university alliances (which are spurring BUSM research grants in an era of restricted growth in biomedical research), represent the schools/departments/sections of Biochemistry, Physiology and Biophysics, Mass Spectrometry, Engineering, Bioinformatics, Cardiology, Epidemiology, and Medicine. In addition, CPC has many relationships and ongoing projects with researchers in the corporate sector.
| Catherine E. Costello, Ph.D. | Principal Investigator | Mass Spectrometry, Proteomics Methods, Unfavorable Metabolic Syndromes | |
| Richard A. Cohen, M.D. | Co-PI, Leader for Vascular Biology Project | Methods for Mouse Studies | |
| Wilson S. Colucci, M.D. | Co-PI, Leader for Clinical Project | Metabolic Predictors of Diastolic Heart Failure | |
| Mark E. McComb, Ph.D. | Director, Cardiovascular Proteomics Core Laboratory | Development and application of mass spectrometry (MS) and proteomics based technologies for the characterization of human disease | |
| Vasan S. Ramachadran, M.D. | Collaborator, BUSM, Framingham Heart Study | Observations in the Offspring Cohort of the Framingham Heart Study | |
| Christian Schöneich, Ph.D. | Chair, Dept. of Pharmaceutical Chemistry, U Kansas | Mechanisms of free radical reactions and protein stability |
