NIHMS Submission and ID Number
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Selected Publications by Trainees
1. Cote GM, Miller TA, Lebrasseur NK, Kuramochi Y, Sawyer DB. Neuregulin-1alpha and
beta isoform expression in cardiac microvascular endothelial cells and function in cardiac
myocytes in vitro. Exp Cell Res. 2005 Nov 15;311(1):135-46. PMID: 16185687
2. Miller TA, LeBrasseur NK, Cote GM, Trucillo MP, Pimentel DR, Ido Y, Ruderman NB,
Sawyer DB. Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes.
Biochem Biophys Res Commun. 2005 Oct 14;336(1):309-15. PMID: 16126172
3. Kuramochi Y, Cote GM, Guo X, Lebrasseur NK, Cui L, Liao R, Sawyer DB. Cardiac
endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis
through neuregulin-1beta/erbB4 signaling. J Biol Chem. 2004 Dec 3;279(49):51141-7.
PMID: 15385548
4. Tanaka Y, Koido S, Xia J, Ohana M, Liu C, Cote GM, Sawyer DB, Calderwood S, Gong
J. Development of antigen-specific CD8+ CTL in MHC class I-deficient mice through CD4
to CD8 conversion. J Immunol. 2004 Jun 15;172(12):7848-58. PMID: 15187169
1. Pimentel DR, Adachi T, Ido Y, Heibeck T, Jiang B, Lee Y, Melendez JA, Cohen RA,
Colucci WS. Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive
oxygen species-dependent Ras S-glutathiolation. J Mol Cell Cardiol. 2006 Oct;41(4):613-
22. PMID: 16806262
2. Sethuraman M, McComb ME, Huang H, Huang S, Heibeck T, Costello CE, Cohen RA.
Isotope-coded affinity tag (ICAT) approach to redox proteomics: identification and
quantitation of oxidant-sensitive cysteine thiols in complex protein mixtures. J Proteome
Res. 2004 Nov-Dec;3(6):1228-33. PMID: 15595732
3. Adachi T, Pimentel DR, Heibeck T, Hou X, Lee YJ, Jiang B, Ido Y, Cohen RA. Sglutathiolation
of Ras mediates redox-sensitive signaling by angiotensin II in vascular
smooth muscle cells. J Biol Chem. 2004 Jul 9;279(28):29857-62. PMID: 15123696
4. Sethuraman M, McComb ME, Heibeck T, Costello CE, Cohen RA. Isotope-coded
affinity tag approach to identify and quantify oxidant-sensitive protein thiols. Mol Cell
Proteomics. 2004 Mar;3(3):273-8. PMID: 14726493
1. Dan Yang*, Donald J. McCrann*, Hao Nguyen, Cynthia St. Hilaire, Ronald A. DePinho,
Matthew R. Jones, Katya Ravid. Increased polyploidy in aortic vascular smooth muscle
cells during aging is marked by cellular senescence. Aging Cell 2007 6:2 257-260.
(*contributed equally)
2. McCrann DJ, Yezefski T, Nguyen HG, Papadantonakis N, Liu H, Wen Q, Crispino JD,
Ravid K. Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere
with erythroid/megakaryocytic lineage development in transgenic mice. Blood. 2008 Apr
15;111(8):4092-5. Epub 2008 Feb 1. PMID: 18245663
3. Yang D, Koupenova M, McCrann DJ, Kopeikina KJ, Kagan HM, Schreiber BM, Ravid
K. The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U S
A. 2008 Jan 15;105(2):792-6. Epub 2008 Jan 9. PMID: 18184815
4. McCrann DJ, Nguyen HG, Jones MR, Ravid K. Vascular smooth muscle cell polyploidy:
an adaptive or maladaptive response? J Cell Physiol. 2008 Jun;215(3):588-92. Review.
PMID: 18181174
5. Papadantonakis N, Makitalo M, McCrann DJ, Liu K, Nguyen HG, Martin G, Patel-Hett
S, Italiano JE, Ravid K. Direct visualization of the endomitotic cell cycle in living
megakaryocytes: differential patterns in low and high ploidy cells. Cell Cycle. 2008
Aug;7(15):2352-6. Epub 2008 May 21. PMID: 18677109
6. Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St Hilaire C, Schreiber BM, Hashimoto
A, Inagaki M, Earnshaw WC, Todokoro K, Ravid K. Vascular smooth muscle cell
polyploidization involves changes in chromosome passenger proteins and an endomitotic
cell cycle. Exp Cell Res. 2005 May 1;305(2):277-91.
1. Ottaviano FG, Handy DE, Loscalzo J. Redox regulation in the extracellular
environment. Circ J. 2008 Jan;72(1):1-16. Review. PMID: 18159092
2. Voetsch B, Jin RC, Bierl C, Benke KS, Kenet G, Simioni P, Ottaviano F, Damasceno
BP, Annichino-Bizacchi JM, Handy DE, Loscalzo J. Promoter polymorphisms in the
plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic
stroke among young adults and children. Stroke. 2007 Jan;38(1):41-9. Epub 2006 Nov
22. PMID: 17122425
3. Ottaviano F, Handy D, Loscalzo J. Overexpression and Purification of the
Selenoprotein Plasma Glutathione Peroxidase. FASEB J: American Society for
Biochemistry and Molecular Biology Washington, DC, April 2007. [published abstract]
1. Csutora P, Peter K, Kilic H, Park KM, Zarayskiy V, Gwozdz T, Bolotina VM. Novel role
for STIM1 as a trigger for calcium influx factor production. J Biol Chem. 2008 May 23;283(21):14524-31. Epub 2008 Mar 12. PMID: 18337241
2. Park KM, Trucillo M, Serban N, Cohen RA, Bolotina VM. Role of iPLA2 and storeoperated
channels in agonist-induced Ca2+ influx and constriction in cerebral,
mesenteric, and carotid arteries. Am J Physiol Heart Circ Physiol. 2008
Mar;294(3):H1183-7. Epub 2007 Dec 21. PMID: 18156193
3. Kristen Park, Peter Csutora, Krisztina Peter and Victoria M Bolotina iPLA2-dependent
activation of store-operated channels is crucial for agonist-induced Ca2+ influx and
constriction in SMCs of cerebral arteries. FASEB J; Phospholipase Meeting, Saxton
River, VT, USA. 2006. [published abstract]
4. Kristen Park, Peter Csutora, Krisztina Peter and Victoria M Bolotina iPLA2-dependent
activation of store-operated channels is crucial for agonist-induced Ca2+ influx and
constriction in SMCs of cerebral arteries. FASEB J; SMC Meeting, Snowmass, CO, USA.
2006. [published abstract]
1. St. Hilaire C, Koupenova M, Carroll SH, Smith BD, Ravid K. TNF-alpha upregulates the
A(2B) adenosine receptor gene: The role of NAD(P)H oxidase 4. Biochem Biophys Res
Commun. 2008 Jul 19. [Epub ahead of print] PMID: 18647598
2. St. Hilaire C, Yang D, Schreiber BM, Ravid K. B-Myb regulates the A(2B) adenosine
receptor in vascular smooth muscle cells. J Cell Biochem. 2008 Apr 15;103(6):1962-74.
PMID: 17979185
3. Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St.
Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD and
Ravid K (2006) The A2B adenosine receptor protects against inflammation and excessive
vascular adhesion. J Clin Invest 116(7):1913-1923.
4. Yang D, McCrann DJ, Nguyen H, St. Hilaire C, DePinho RA, Jones MR, Ravid K.
Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by
cellular senescence. Aging Cell. 2007 Apr;6(2):257-60. Epub 2007 Feb 7.
PMID: 17291294
5. Hurtado PA, Vora S, Sume SS, Yang D, St. Hilaire C, Guo Y, Palamakumbura AH,
Schreiber BM, Ravid K, Trackman PC. Lysyl oxidase propeptide inhibits smooth muscle
cell signaling and proliferation. Biochem Biophys Res Commun. 2008 Feb 1;366(1):156-
61. Epub 2007 Dec 3. PMID: 18060869
6. Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St. Hilaire C, Schreiber BM,
Hashimoto A, Inagakid M, Earnshawe WC, Todokorob K et al: Vascular smooth muscle
cell polyploidization involves changes in chromosome passenger proteins and an
endomitotic cell cycle. Experimental Cell Research 2005, 305:277-291.
1. St Hilaire C, Koupenova M, Carroll SH, Smith BD, Ravid K. TNF-alpha upregulates the
A(2B) adenosine receptor gene: The role of NAD(P)H oxidase 4. Biochem Biophys Res
Commun. 2008 [Epub ahead of print] PMID: 18647598
2. Yang D, Koupenova M, McCrann DJ, Kopeikina KJ, Kagan HM, Schreiber BM, Ravid
K. The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U
Conferences Attended by Trainees (and poster/oral presentations):
Coté, G.M.
- Gregory M. Coté, Thomas A. Miller, Douglas B. Sawyer. Differential Effects of Neuregulin-1a and b in Neonatal Rat Ventricular Myocytes in Culture. Experimental Biology Meeting, Washington, DC.. April 2004.
Heibeck, T.
- Heibeck T., McComb M.E., Haung H., Schöneich C., Cohen R.A., Costello C.E. Development of a protein 3-nitrotyrosine identification method using solid phase capture. American Society for Mass Spectrometry 53rd Annual Conference, San Antonio, TX. 2005.
- Heibeck, T., McComb, M.E., Schöneich, C., Cohen R.A., Costello, C.E. Affinity Labeling and solid phase capture Methods to Detect Site of 3-Nitrotyrosine Protein Modification. Oxidative Post-Translational Modifications in the Cardiovascular System, Boston University School of Medicine, Boston, MA. October 6 8, 2004.
- Heibeck T., McComb M.E., Haung H., Huang S., Schöneich C., Cohen R.A., Costello C.E. Development of a protein 3-nitrotyrosine identification method using affinity labeling and solid phase capture. American Society for Mass Spectrometry 52nd Annual Conference, Nashville, TN. 2004.
- Pimentel D. R.*, Adachi T., Heibeck T. H., Jiang B., Ido Yasuo, Cohen R. A., Colucci W. S. Role of Mitochondria in ROS-Dependent ras-Mek-Erk 1/2 Activation and Hypertrophy in response to Mechanical Strain in Cardiac Myocytes. American Heart Association Conference, Orlando, FL. 2003.
- Heibeck T., Schoneich C., McComb M.E., Lim A., Cohen R. A., Costello C.E. A nitro-tyrosine specific ICAT method. American Society for Mass Spectrometry 51st Annual Conference, Montreal, Canada. 2003.
McCrann, D.J.
- McCrann, DJ,. A Role for NADPH Oxidases in Control of Megakaryocyte Endomitosis and Polyploidy. Gordon Research Conference: Cell Biology Of Megakaryocytes & Platelets, Ventura, CA. March 4-9, 2007.
- McCrann, DJ,. Conditional Lineage Specific Expression of Survivin in Transgenic Mice Does Not Affect Megakaryocyte ploidy or Platelet Levels. Gordon Research Conference: Cell Biology Of Megakaryocytes & Platelets, Ventura, CA. March 4-9, 2007.
- McCrann, DJ, . Increased Polyploidy in Aortic Vascular Smooth Muscle Cells During Aging is Marked by Upregulated NOX4 and Cellular Senescence. Molecular Biology of the Vasculature, Keystone, CO. Apr 2-7, 2006.
- McCrann, DJ,. Increased Polyploidy in Aortic Vascular Smooth Muscle Cells During Aging is Marked by Upregulated NOX4 and Cellular Senescence. Twelfth Annual Henry I. Russek Student Achievement Day, Boston, MA. May 5, 2006.
- McCrann, DJ,. Oxidative Post-Translational Modifications in the Cardiovascular System. Boston, MA. Oct. 6-8, 2004.
Ottaviano, F.
- Ottaviano F, Handy D, Loscalzo J. Overexpression and Purification of the Selenoprotein Plasma Glutathione Peroxidase. FASEB: American Society for Biochemistry and Molecular Biology Washington, DC, April 2007.
- Ottaviano F, Handy D, Loscalzo J. Overexpression and Purification of the Selenoprotein Plasma Glutathione Peroxidase. Boston University Science and Engineering Symposium, Boston, MA, April 2007.
- Ottaviano F, Handy D, Loscalzo J. Overexpression and Purification of the Selenoprotein Plasma Glutathione Peroxidase. BWH Cardiovascular, Diabetes, and Metabolic Disorders Research Center Retreat, Boston, MA, February 2007.
- Ottaviano F, Handy D, Loscalzo J. Overexpression and Purification of the Selenoprotein Plasma Glutathione Peroxidase. BUMC Department of Medicine Evans Day, Boston, MA, November 2006.
- Oxidative Post-Translational Modifications of Proteins in Cardiovascular Disease (OPTM) Symposium, BUMC Cardiovascular Proteomics Center, 2006
- Oxidative Post-Translational Modifications of Proteins in Cardiovascular Disease (OPTM) Symposium, BUMC Cardiovascular Proteomics Center, 2004
- Oxidative Stress, FASEB Post-Translational Modifications in the Cardiovascular System, Boston University School of Medicine, Boston, MA, October 6 – 8, 2004.
- FASEB, San Diego, CA. April 2-6, 2005.
St. Hilaire, C.
- St. Hilaire, C., Yang, D. and Ravid, K./Hazony, Y., Lu, J., St. Hilaire, C. and Ravid, K. A successful search for a lineage specific genetic signature that controls gene expression: the megakaryocyte and vascular smooth muscle examples. Thirteenth Annual Henry I. Russek Student Achievement Day, Boston University School of Medicine, Boston, MA. 2007.
- St. Hilaire, C., Yang, D., Ravid, K. The A2B Adenosine Receptor gene is upregulated by the proliferation state: the role of B-Myb protein. Experimental Biology/FASEB, San Francisco, CA. April 1-5, 2006.
- St. Hilaire, C., Yang, D. and Ravid, K. The A2B adenosine receptor gene is regulated by the proliferation state: the role of B-Myb protein. Twelfth Annual Henry I. Russek Student Achievement Day, Boston University School of Medicine, Boston, MA. 2006.
- St. Hilaire, C., Yang, D., Jones, M. and Ravid, K. Regulation of the A2B adenosine receptor gene. Eleventh Annual Henry I. Russek Student Achievement Day, Boston University School of Medicine, Boston, MA. 2005.
- The Small RNA Revolution: Biology, Technology and Disease. MIT Center for Cancer Research Third Annual Symposium, Kresge Auditorium at MIT. June 18th, 2004.
- Oxidative Post-Translational Modifications in the Cardiovascular System. Boston University Cardiovascular Proteomics Center. Oct. 6-8, 2004.
Park, K.
- Park K.M., Trucillo M., Serban N., Cohen R.A., Bolotina V.M. iPLA2-dependent activation of store-operated channels is crucial for agonist-induced Ca2+ influx and constriction in cerebral, mesenteric and carotid arteries. Biophysical Society Annual Meeting, Long Beach, Ca, USA, 2005.
- Kristen Park, Peter Csutora, Krisztina Peter and Victoria M Bolotina iPLA2-dependent activation of store-operated channels is crucial for agonist-induced Ca2+ influx and constriction in SMCs of cerebral arteries. FASEB Phospholipase Meeting, Saxton River, VT, USA. 2006.
- Kristen Park, Peter Csutora, Krisztina Peter and Victoria M Bolotina iPLA2-dependent activation of store-operated channels is crucial for agonist-induced Ca2+ influx and constriction in SMCs of cerebral arteries. FASEB SMC Meeting, Snowmass, CO USA. 2006
- Kristen Park, Peter Csutora, Krisztina Peter and Victoria M Bolotina iPLA2-dependent activation of store-operated channels is crucial for agonist-induced Ca2+ influx and constriction in SMCs of cerebral arteries. Evans Day, Boston University, Boston, MA, USA. 2006.
Sullivan, C.
- Sullivan, C.P., Raymondjean, M. and Schreiber, B.M. Acute phase serum amyloid A induces expression of the rat type IIA Phsopholipase A2 gene. Thirteenth Annual H. Russek Student Achievement Day, Boston University School of Medicine, May 11, 2007.
Walk, M.
- Thirteenth Annual H. Russek Student Achievement Day, Boston University School of Medicine, May 11, 2007
