Dr. Fried is Professor and Director of Translational Adipose Biology and Obesity in the Diabetes, Obesity and Metabolism Institute. She earned an A.B. in Biology from Barnard College (1974), a M.S. in Human Nutrition from the Institute of Human Nutrition, Columbia College of Physicians and Surgeons and a Ph.D. in Nutritional Biochemistry from Columbia University (1980). After post-doctoral work in Endocrinology at Emory University, and in Lipid Biochemistry at the Medical College of Pennsylvania, she returned to NYC to become a Research Associate at the New York Obesity Center. From 1986-1990, she was an Assistant Professor in the Laboratory of Human Behavior and Metabolism at Rockefeller University, followed by faculty positions at Rutgers University and the University of Maryland School of Medicine. At Maryland she was the founding director of a NIDDK-funded Clinical Nutrition Research Center. From 2009-2016 Dr. Fried was a Professor at Medicine and Biochemistry at the Boston University School of Medicine (BUSM). She was also the Director of the Graduate Program in Nutrition and Metabolism, and Director of the NIH NIDDK-funded Boston Obesity and Nutrition Research during this time. Her work has been well-funded by the NIH and the American Diabetes Association, among others, for the past 25 years.
- Director, Boston Nutrition and Obesity Research Center (BNORC), Boston University School of Medicine
- Director, Adipose Biology and Nutrient Metabolism Core, BNORC, Boston University School of Medicine
- Director, Affinity Research Collaborative on “Sex differences in Adipose Tissue and Obesity-related Metabolic Diseases”, Boston University School of Medicine
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
- Boston Medical Center
- Columbia University, PhD
- Columbia University College of Physicians and Surgeons, MS
- Barnard College, AB
- Published on 1/18/2018
Cuffe H, Liu M, Key CC, Boudyguina E, Sawyer JK, Weckerle A, Bashore A, Fried SK, Chung S, Parks JS. Targeted Deletion of Adipocyte Abca1 (ATP-Binding Cassette Transporter A1) Impairs Diet-Induced Obesity. Arterioscler Thromb Vasc Biol. 2018 Jan 18. PMID: 29348118.
- Published on 6/25/2017
Divoux A, Xie H, Li JL, Karastergiou K, Perera RJ, Chang RJ, Fried SK, Smith SR. MicroRNA-196 Regulates HOX Gene Expression in Human Gluteal Adipose Tissue. Obesity (Silver Spring). 2017 Aug; 25(8):1375-1383. PMID: 28649807.
- Published on 6/12/2017
Bredella MA, Karastergiou K, Bos SA, Gerweck AV, Torriani M, Fried SK, Miller KK. GH administration decreases subcutaneous abdominal adipocyte size in men with abdominal obesity. Growth Horm IGF Res. 2017 Aug; 35:17-20. PMID: 28628810.
- Published on 1/1/2017
Karastergiou K, Fried SK. Cellular Mechanisms Driving Sex Differences in Adipose Tissue Biology and Body Shape in Humans and Mouse Models. Adv Exp Med Biol. 2017; 1043:29-51. PMID: 29224089.
- Published on 12/22/2016
Pickering RT, Lee MJ, Karastergiou K, Gower A, Fried SK. Depot Dependent Effects of Dexamethasone on Gene Expression in Human Omental and Abdominal Subcutaneous Adipose Tissues from Obese Women. PLoS One. 2016; 11(12):e0167337. PMID: 28005982.
- Published on 12/9/2016
Fried SK. Adipocyte size redux. Obesity (Silver Spring). 2017 Jan; 25(1):15. PMID: 27935267.
- Published on 11/22/2016
Wu Y, Lee MJ, Ido Y, Fried SK. High-fat diet-induced obesity regulates MMP3 to modulate depot- and sex-dependent adipose expansion in C57BL/6J mice. Am J Physiol Endocrinol Metab. 2017 Jan 01; 312(1):E58-E71. PMID: 27879248.
- Published on 10/31/2016
Cederquist CT, Lentucci C, Martinez-Calejman C, Hayashi V, Orofino J, Guertin D, Fried SK, Lee MJ, Cardamone MD, Perissi V. Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Mol Metab. 2017 Jan; 6(1):125-137. PMID: 28123943.
- Published on 5/13/2016
Lee MJ, Yang RZ, Karastergiou K, Smith SR, Chang JR, Gong DW, Fried SK. Low expression of the GILZ may contribute to adipose inflammation and altered adipokine production in human obesity. J Lipid Res. 2016 Jul; 57(7):1256-63. PMID: 27178044.
- Published on 3/26/2016
Karastergiou K, Bredella MA, Lee MJ, Smith SR, Fried SK, Miller KK. Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape. Obesity (Silver Spring). 2016 May; 24(5):1090-6. PMID: 27015877.
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