Patrycja Dubielecka-Szczerba, PhD

Assistant Professor, Medicine

Patrycja Dubielecka-Szczerba
Working Remotely – Contact MED

Biography

Dr. Dubielecka is an Assistant Professor of Medicine at the Alpert Medical School of Brown University and head of the Signal Transduction Lab. She is also an Assistant Professor of Medicine at the Boston University School of Medicine, and holds an adjunct appointment in the Division of Hematology/Oncology in the Department of Medicine at Rhode Island Hospital.

Dr. Dubielecka received her undergraduate and PhD degrees from the University of Wroclaw, Poland. She was a scholar of the Socrates/Erasmus Programme established by the European Commission, and trained at the University of Helsinki, Finland and at Charles University in Hradec Kralove, Czech Republic. Dr. Dubielecka did her postdoctoral training in the Lindsley F. Kimball Research Institute in New York. During her training she collaborated closely with colleagues at the University of Michigan, Ann Arbor and Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany. Dr. Dubielecka received extensive training in biochemistry, biophysics, cell biology, and protein chemistry. Prior to joining the faculty at Brown University, Dr. Dubielecka was a project leader in the NIH Center of Biomedical Research Excellence (COBRE) in Stem Cell Biology at the Roger Williams Medical Center, Boston University School of Medicine. Dr. Dubielecka has mentored undergraduate students, medical students, residents, fellows, and post-doctoral fellows.

Other Positions

  • Roger Williams Medical Center

Education

  • University of Wroclaw, PhD
  • University of Wroclaw, MSc
  • University of Wroclaw, BS

Publications

  • Published on 1/6/2016

    Du J, Zhang L, Wang Z, Yano N, Zhao YT, Wei L, Dubielecka-Szczerba P, Liu PY, Zhuang S, Qin G, Zhao TC. Exendin-4 induces myocardial protection through MKK3 and Akt-1 in infarcted hearts. Am J Physiol Cell Physiol. 2016 Feb 15; 310(4):C270-83. PMID: 26739490.

    Read at: PubMed
  • Published on 4/4/2014

    Chorzalska A, Salloum I, Shafqat H, Khan S, Marjon P, Treaba D, Schorl C, Morgan J, Bryke CR, Falanga V, Zhao TC, Reagan J, Winer E, Olszewski AJ, Al-Homsi AS, Kouttab N, Dubielecka PM. Low expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl-induced leukemia. Leukemia. 2014 Nov; 28(11):2165-77. PMID: 24699303.

    Read at: PubMed
  • Published on 1/1/2014

    Bartos A, Dubielecka PM. The emerging role of Bcr-Abl-induced cystoskeletal remodeling in systemic persistence of leukemic stem cells. Curr Drug Deliv. 2014; 11(5):582-91. PMID: 23517626.

    Read at: PubMed
  • Published on 4/8/2013

    Toporkiewicz M, Grzybek M, Meissner J, Michalczyk I, Dubielecka PM, Korycka J, Seweryn E, Sikorski AF. Release of an ~55kDa fragment containing the actin-binding domain of ß-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1. Arch Biochem Biophys. 2013 Jul 15; 535(2):205-13. PMID: 23578573.

    Read at: PubMed
  • Published on 11/27/2012

    Michalczyk I, Sikorski AF, Kotula L, Junghans RP, Dubielecka PM. The emerging role of protein kinase C? in cytoskeletal signaling. J Leukoc Biol. 2013 Mar; 93(3):319-27. PMID: 23192428.

    Read at: PubMed
  • Published on 9/28/2012

    Zhang L, Chen B, Zhao Y, Dubielecka PM, Wei L, Qin GJ, Chin YE, Wang Y, Zhao TC. Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts. J Biol Chem. 2012 Nov 16; 287(47):39338-48. PMID: 23024362.

    Read at: PubMed
  • Published on 9/3/2012

    Xiong X, Chorzalska A, Dubielecka PM, White JR, Vedvyas Y, Hedvat CV, Haimovitz-Friedman A, Koutcher JA, Reimand J, Bader GD, Sawicki JA, Kotula L. Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice. Oncogenesis. 2012; 1:e26. PMID: 23552839.

    Read at: PubMed
  • Published on 5/1/2012

    Hossain S, Dubielecka PM, Sikorski AF, Birge RB, Kotula L. Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton. Genes Cancer. 2012 May; 3(5-6):402-13. PMID: 23226578.

    Read at: PubMed
  • Published on 4/11/2011

    Dubielecka PM, Ladwein KI, Xiong X, Migeotte I, Chorzalska A, Anderson KV, Sawicki JA, Rottner K, Stradal TE, Kotula L. Essential role for Abi1 in embryonic survival and WAVE2 complex integrity. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7022-7. PMID: 21482783.

    Read at: PubMed
  • Published on 4/3/2011

    Dubielecka PM, Hwynn N, Sengun C, Lee S, Lomas-Francis C, Singer C, Fernandez HH, Walker RH. Two McLeod patients with novel mutations in XK. J Neurol Sci. 2011 Jun 15; 305(1-2):160-4. PMID: 21463873.

    Read at: PubMed

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