Dr. Ieong is an Assistant Professor in the Department of Medicine. He attends in the Medical Intensive Care Unit and on the Pulmonary Consult service of Boston Medical Center. He sees patients in the Pulmonary and Allergy outpatient clinic and oversees the cardiopulmonary exercise testing program.
Dr. Ieong’s focus is on translational medicine. His research focuses on the innate immunity of the lung in response to infection, particularly in the context of immune compromise such as HIV-infection. His clinical expertise is in critical care medicine and the administration of intensive care units.
Dr. Ieong is a NIH-funded Principal Investigator with research focused on the role of the alveolar macrophage and monocyte in host immunity and HIV-related lung pathogenesis. Projects in the lab study the redox regulation of HIV expression in alveolar macrophages; the role of IL-16 in HIV-infection of alveolar macrophages; and, HIV-induced impairment of alveolar macrophage handling of C. neoformans. He is an experienced research bronchoscopist and collaborates with a number of investigators to provide primary lung cells and lavage for study. He is a member of the Pulmonary Immunology Group and the Center for HIV/AIDS Care and Research.
Research special interests include:
-HIV pathogenesis in the lung
-Redox cell signaling pathways
-Alveolar macrophage biology
-Innate immunity of the lung
Clinical special interests include:
-HIV-related lung disease
-General pulmonary medicine
- Active Staff Privileges, Pulmonary, Allergy, Sleep & Critical Care Medicine, Medicine, Boston Medical Center
- University of Illinois, MD
- Oberlin College, BA
- Published on 6/30/2017
Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez NP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ, Mizgerd JP, Jones MR. The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses. PLoS One. 2017; 12(6):e0179797. PMID: 28665939.
- Published on 3/17/2015
Man A, Davidyock T, Ferguson LT, Ieong M, Zhang Y, Simms RW. Changes in forced vital capacity over time in systemic sclerosis: application of group-based trajectory modelling. Rheumatology (Oxford). 2015 Aug; 54(8):1464-71. PMID: 25784774.
- Published on 10/9/2014
Hyatt LD, Wasserman GA, Rah YJ, Matsuura KY, Coleman FT, Hilliard KL, Pepper-Cunningham ZA, Ieong M, Stumpo DJ, Blackshear PJ, Quinton LJ, Mizgerd JP, Jones MR. Myeloid ZFP36L1 does not regulate inflammation or host defense in mouse models of acute bacterial infection. PLoS One. 2014; 9(10):e109072. PMID: 25299049.
- Published on 6/15/2010
Walkey AJ, Ieong M, Alikhan M, Farber HW. Cardiopulmonary exercise testing with right-heart catheterization in patients with systemic sclerosis. J Rheumatol. 2010 Sep; 37(9):1871-7. PMID: 20551099.
- Published on 6/4/2008
Nicol MQ, Mathys JM, Pereira A, Ollington K, Ieong MH, Skolnik PR. Human immunodeficiency virus infection alters tumor necrosis factor alpha production via Toll-like receptor-dependent pathways in alveolar macrophages and U1 cells. J Virol. 2008 Aug; 82(16):7790-8. PMID: 18524817.
- Published on 1/1/2008
Ieong MH, Farber H. HIV and Pulmonary Hypertension. In: UpToDate, Rose, BD (Ed). UpToDate. Wellesley, MA. 2008.
- Published on 4/1/2006
Lee J, Remold HG, Ieong MH, Kornfeld H. Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway. J Immunol. 2006 Apr 1; 176(7):4267-74. PMID: 16547264.
- Published on 1/1/2006
Ieong MH, Farber H. Noninfectious Pulmonary Complications of HIV. Clin Pulm Med. 2006; 13(3):194-202.
- Published on 6/1/2002
Summer R, Zacks J, Ieong M, O'Regan A. Cough, fever and weight loss in a young male. Eur Respir J. 2002 Jun; 19(6):1210-3. PMID: 12108878.
- Published on 9/1/2000
Ieong MH, Reardon CC, Levitz SM, Kornfeld H. Human immunodeficiency virus type 1 infection of alveolar macrophages impairs their innate fungicidal activity. Am J Respir Crit Care Med. 2000 Sep; 162(3 Pt 1):966-70. PMID: 10988114.
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