Kenneth Walsh, PhD

Adjunct Professor, Medicine

Kenneth Walsh
617.414.2390
700 Albany St Ctr for Adv Biomed Res

Biography

My laboratory examines molecular events that drive cardiovascular cell growth, differentiation and apoptosis. Over the past decade my laboratory has been investigating mechanisms of inter-tissue communication and how these systems contribute to physiological versus pathological tissue growth in the cardiovascular system.

Other Positions

  • Director of Whitaker Cardiovascular Institute, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences

Education

  • University of California, Berkeley, PhD
  • Bowling Green State University, BS

Publications

  • Published on 9/4/2018

    Sano S, Wang Y, Walsh K. Clonal Hematopoiesis and Its Impact on Cardiovascular Disease. Circ J. 2018 Sep 04. PMID: 30185689.

    Read at: PubMed
  • Published on 6/10/2018

    Maruyama S, Wu CL, Yoshida S, Zhang D, Li PH, Wu F, Parker Duffen J, Yao R, Jardin B, Adham IM, Law R, Berger J, Di Marchi R, Walsh K. Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models. J Am Heart Assoc. 2018 Jun 10; 7(12). PMID: 29887522.

    Read at: PubMed
  • Published on 5/4/2018

    Sano S, Oshima K, Wang Y, Katanasaka Y, Sano M, Walsh K. CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease. Circ Res. 2018 Jul 20; 123(3):335-341. PMID: 29728415.

    Read at: PubMed
  • Published on 2/27/2018

    Sano S, Oshima K, Wang Y, MacLauchlan S, Katanasaka Y, Sano M, Zuriaga MA, Yoshiyama M, Goukassian D, Cooper MA, Fuster JJ, Walsh K. Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1ß/NLRP3 Inflammasome. J Am Coll Cardiol. 2018 Feb 27; 71(8):875-886. PMID: 29471939.

    Read at: PubMed
  • Published on 2/2/2018

    Fuster JJ, Walsh K. Somatic Mutations and Clonal Hematopoiesis: Unexpected Potential New Drivers of Age-Related Cardiovascular Disease. Circ Res. 2018 Feb 02; 122(3):523-532. PMID: 29420212.

    Read at: PubMed
  • Published on 1/1/2018

    Seki M, Powers JC, Maruyama S, Zuriaga MA, Wu CL, Kurishima C, Kim L, Johnson J, Poidomani A, Wang T, Muñoz E, Rajan S, Park JY, Walsh K, Recchia FA. Acute and Chronic Increases of Circulating FSTL1 Normalize Energy Substrate Metabolism in Pacing-Induced Heart Failure. Circ Heart Fail. 2018 Jan; 11(1):e004486. PMID: 29317401.

    Read at: PubMed
  • Published on 12/11/2017

    Zuriaga MA, Fuster JJ, Farb MG, MacLauchlan S, Bretón-Romero R, Karki S, Hess DT, Apovian CM, Hamburg NM, Gokce N, Walsh K. Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation. Sci Rep. 2017 Dec 11; 7(1):17326. PMID: 29229927.

    Read at: PubMed
  • Published on 8/30/2017

    Neppl RL, Wu CL, Walsh K. lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy. J Cell Biol. 2017 Nov 06; 216(11):3497-3507. PMID: 28855249.

    Read at: PubMed
  • Published on 8/12/2017

    Fuster JJ, Maclauchlan S, Zuriaga MA, Polackal MN, Walsh K. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis in hyperlipidemic mice. Atherosclerosis. 2017 Aug; 263:e14. PMID: 29365557.

    Read at: PubMed
  • Published on 8/12/2017

    Zuriaga MA, Fuster JJ, Maclauchlan S, Gokce N, Walsh K. Coordinated activation of WNT/planar cell polarity signaling in inflamed visceral fat of obese individuals. Atherosclerosis. 2017 Aug; 263:e8. PMID: 29366230.

    Read at: PubMed

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