Dr. Steiling is an Assistant Professor of Medicine. She sees patients in the multidisciplinary Thoracic Oncology Clinic and attends in the Medical Intensive Care Unit at Boston Medical Center.
Dr. Steiling’s research focuses on applying high-throughput genomic tools and emerging computational methods to develop improved diagnostics, prognostics, and risk stratification tools for phenotypically complex lung diseases such as chronic obstructive pulmonary disease (COPD) and lung cancer. Dr. Steiling’s primary research involves gene expression profiling of the airway epithelium from individuals with COPD in order to understand the molecular mechanisms of this disease and its relationship to lung cancer. She has also worked to apply airway gene expression profiling to the diagnosis of lung cancer, to understand the relationship between smoking-induced changes in gene expression in the bronchial airway and the upper airway, and to elucidate the relationship between smoking-induced changes in airway gene and protein expression.
Research interests include:
-Airway gene expression
-Chronic Obstructive Pulmonary Disease (COPD)
Clinical interests include:
-Critical Care Medicine
- Member, Bioinformatics Graduate Program, Boston University
- Boston University School of Medicine, MD
- Boston University, MSc
- Boston College, BS
- Published on 5/6/2019
Hijazi K, Malyszko B, Steiling K, Xiao X, Liu G, Alekseyev YO, Dumas YM, Hertsgaard L, Jensen J, Hatsukami D, Brooks DR, O'Connor G, Beane J, Lenburg ME, Spira A. Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation. Sci Rep. 2019 May 06; 9(1):6978. PMID: 31061400.
- Published on 4/25/2019
Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M. Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD. Eur Respir J. 2019 Apr; 53(4). PMID: 30846474.
- Published on 1/1/2019
Hersh CP, Adcock IM, Celedón JC, Cho MH, Christiani DC, Himes BE, Kaminski N, Mathias RA, Meyers DA, Quackenbush J, Redline S, Steiling KA, Tabor HK, Tobin MD, Wurfel MM, Yang IV, Koppelman GH. High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019 Jan; 16(1):1-16. PMID: 30592451.
- Published on 12/1/2018
Iaccarino JM, Steiling KA, Wiener RS. Lung Cancer Screening in a Safety-Net Hospital: Implications of Screening a Real-World Population versus the National Lung Screening Trial. Ann Am Thorac Soc. 2018 Dec; 15(12):1493-1495. PMID: 30199643.
- Published on 4/6/2018
Abston E, Novaco R, Hon S, Scalera J, Steiling K. Breath of relief: apparent pulmonary nodule due to heterotopic ossification. Clin Case Rep. 2018 Jun; 6(6):1174-1175. PMID: 29881589.
- Published on 2/9/2018
Muñoz-Largacha JA, Steiling KA, Kathuria H, Charlot M, Fitzgerald C, Suzuki K, Litle VR. Initial surgical experience following implementation of lung cancer screening at an urban safety net hospital. J Thorac Cardiovasc Surg. 2018 Jun; 155(6):2674-2681. PMID: 29534906.
- Published on 12/21/2017
Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M. Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression. Respir Res. 2017 12 21; 18(1):213. PMID: 29268739.
- Published on 1/1/2017
Christenson SA, Steiling K. Shifting from Correlation to Causation: Challenges for the Future of Unbiased Molecular Studies in Inflammatory Lung Disease. Am J Respir Crit Care Med. 2017 01 01; 195(1):5-7. PMID: 28035851.
- Published on 11/1/2016
Bhatt N, Sloan JM, O'Hara CJ, Oommen R, Steiling K, Litle VR. Extranodal Marginal Zone Endobronchial Lymphoma Associated With Hepatitis C. Ann Thorac Surg. 2016 Nov; 102(5):e407-e408. PMID: 27772593.
- Published on 10/14/2015
Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, Rothman N, Spira A, Lan Q. Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal. Carcinogenesis. 2015 Dec; 36(12):1494-501. PMID: 26468118.
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