John H. Schwartz, M.D. is a Professor of Medicine and has been a member of the Renal Section at BUSM since 1977. In addition to teaching and conducting research, Dr. Schwartz also mentors physician scientists at GMS. Dr. Schwartz grew up in Fall River, Ma and attended BU for his undergraduate degree in Biology. As an undergraduate, Dr. Schwartz became interested in basic research and was involved in an NSF sponsorship program for undergraduates. He went on to earn his MD at the New York University School of Medicine. He then completed an internship-residency in Internal Medicine and a Post Doctoral Fellowship in Nephrology at the Beth Israel Hospital in Boston. He trained in the laboratory of Dr. Philip Steinmetz at Harvard Medical School. In 1971 he became a staff member of the renal unit at the Walter Reed Army Institute of Research, eventually acting as chief of the unit from 1973 to 1977. Dr. Schwartz has made research contributions in a number of areas including the cellular regulation of H+ transport in renal epithelia, coupling in excitable cells and pathogenesis of acute renal failure. His research is supported by grants from NIH.
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
- Active Staff Privileges, Nephrology, Medicine, Boston Medical Center
- New York University, MD
- Boston University, BA
- Published on 9/12/2017
Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC. Correction for Wang et al., "Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death". Mol Cell Biol. 2017 Oct 01; 37(19). PMID: 28899998.
- Published on 9/2/2015
Arafa E, Bondzie PA, Rezazadeh K, Meyer RD, Hartsough E, Henderson JM, Schwartz JH, Chitalia V, Rahimi N. TMIGD1 is a novel adhesion molecule that protects epithelial cells from oxidative cell injury. Am J Pathol. 2015 Oct; 185(10):2757-67. PMID: 26342724.
- Published on 11/6/2014
Coon SD, Rajendran VM, Schwartz JH, Singh SK. Glucose-dependent insulinotropic polypeptide-mediated signaling pathways enhance apical PepT1 expression in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 1; 308(1):G56-62. PMID: 25377315.
- Published on 9/26/2013
Coon SD, Schwartz JH, Rajendran VM, Jepeal L, Singh SK. Glucose-dependent insulinotropic polypeptide regulates dipeptide absorption in mouse jejunum. Am J Physiol Gastrointest Liver Physiol. 2013 Nov 15; 305(10):G678-84. PMID: 24072682.
- Published on 3/4/2013
Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC. Nucleophosmin, a critical Bax cofactor in ischemia-induced cell death. Mol Cell Biol. 2013 May; 33(10):1916-24. PMID: 23459946.
- Published on 3/6/2012
Patel VA, Feng L, Lee DJ, Massenburg D, Pattabiraman G, Antoni A, Schwartz JH, Lieberthal W, Rauch J, Ucker DS, Levine JS. Recognition-dependent signaling events in response to apoptotic targets inhibit epithelial cell viability by multiple mechanisms: implications for non-immune tissue homeostasis. J Biol Chem. 2012 Apr 20; 287(17):13761-77. PMID: 22396534.
- Published on 1/26/2012
Gall JM, Wang Z, Liesa M, Molina A, Havasi A, Schwartz JH, Shirihai O, Borkan SC, Bonegio RG. Role of mitofusin 2 in the renal stress response. PLoS One. 2012; 7(1):e31074. PMID: 22292091.
- Published on 3/23/2011
Gall JM, Wong V, Pimental DR, Havasi A, Wang Z, Pastorino JG, Bonegio RG, Schwartz JH, Borkan SC. Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress. Kidney Int. 2011 Jun; 79(11):1207-16. PMID: 21430642.
- Published on 1/26/2011
Wang Z, Gall JM, Bonegio RG, Havasi A, Hunt CR, Sherman MY, Schwartz JH, Borkan SC. Induction of heat shock protein 70 inhibits ischemic renal injury. Kidney Int. 2011 Apr; 79(8):861-70. PMID: 21270764.
- Published on 11/1/2010
Schwartz JH, Alexander EA. Adaptation of intercalated cells along the collecting duct to systemic acid/base changes. Kidney Int. 2010 Nov; 78(10):949-51. PMID: 21030969.
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