Principal Investigator

10-3009-PHARMAHEAD_Ikezu-116Tsuneya Ikezu, MD/PhD
Awarded Alzheimer’s Art Quilt Institute 2013 Research awardUpdates: Received the award from Coins for Alzheimer’s Research Trust for 2014Updates: Received the award from Alzheimer’s association for 2014Updates: Received the award from Massachusetts neuroscience consortium for 2014

Research Staff

IkezuSeiko1-150x150Seiko Ikezu, MD – Senior Scientist
Research: Seiko’s research is focused on genetic and pharmacological modulation of protein kinases, namely tau-tubulin kinases(TTBK), which are  involved in aggregation of neuropathogenic protein, such as microtubule-associated protein tau, alpha-synuclein, and TDP-43.  Phosphorylation of the amyloidgenic proteins are found in the Ubiquitin-positive inclusion bodies of Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease and amyotrophic lateral sclerosis. TTBK1 and 2 are potential therapeutic target of the proteinopathy-related neurodegeneration.

Graduate Students

MVarnum-150x150Megan Varnum (PhD student, Program in Biomolecular Pharmacology)
Research: Megan’s research focuses on Traumatic Brain Injury (TBI) using the blast mouse models and investigate the role of the inflammation and behavioral deficits. She is also working on the role of CD200 in Alzheimer’s disease. Megan recently authored a review article on microglial activation phenotypes on neurodegenerative disorders.
maya_woodbury_portrait-150x150Maya Woodbury PhD student, Graduate Program for Neuroscience/Program in Biomolecular Pharmacology
Research: Maya is studying the molecular characterization of growth factors and glia-derived cytokines and their effect on neuronal development, especially focusing on Autism Spectrum Disorders and Down Syndrome.Updates: Received PhRMA Foundation 2014 Pre Doctoral Fellowship in Pharmacology & ToxicologyUpdates: Maya was recently chosen as one out of 10 recipients for an SFN Travel Award.

Undergraduate Students

LacinLacin Koro (BU Neuroscience Major)
 Received Howard Hughes Medical Institute Summer Research Scholarship
 Received the Howard Hughes Medical Institute travel award for the Society for Neuroscience meetingUpdates: Lacin is a recipient of UROP Student Research Award in Spring and Fall in 2013, and Spring and Summer in 2014, and “UROP FROG Award” in Fall in 2014.

Hnery PicPin-Hao “Henry” Chao (BU BME Major)Updates: Henry is working on his senior project: ” Fabrication of Microfluidics Chip for Monitoring Neural Network Development”. He is also involved in Autism study.Updates: Henry is a recipient of “UROP FROG award” in Fall in 2014.   
Lisa_PicLisa Nguyen (BU BME Major)Updates: Lisa has been involved in “TREM2 study”.Updates: Lisa is a sophomore at BU BME program. She was awarded a summer fellowship from Jack Kent Cooke Foundation May 2014.


DSC_5178-Hirohide-Asai1-150x150Hirohide Asai, MD/PhD, Postdoctoral Fellow
Research: Hiro is studying the molecular mechanism of axonal degeneration and tauopathy development in transgenic mouse models of Alzheimer’s disease.Updates: Received BrightFocus Foundation 2013 Research Award for Alzheimer’s DiseaseUpdates: Selected for oral presentation at 11th Annual BU Alzheimer’s Disease Research DayUpdates: Received best oral presentation award at the 55th annual meeting of the Japanese Society of Neurology in May.
Ingraham-KatieKaitlin Ingraham, BA
Kaitlin was accepted into the UCLA Graduate ACCESS Program.
DSC_5183-Rob-Freilich1-150x150Robert W. Freilich (MD/PhD student)
Research: Rob’s research is aimed at understanding how microRNAs influence the neuroimmune response in the CNS, focused specifically on microglia and on inflammatory regulation of adult hippocampal neurogenesis.Updates: Received PhRMA Foundation 2012 Paul Calabresi Medical Student FellowshipUpdates: Received 2013 Henry I. Russek Student Achievement First PrizeUpdates: Successfully defended thesis in May 2013
tessaTessa Abagis, BA
Tessa completed honors thesis study at BU and is currently Clinical Research Assistant in the Depression Center at University of Michigan. Tessa has been working on a project entitled “Imaging biomarkers for transcranial magnetic stimulation treatment of depression.”

JDBJonathan Boucher, BS


Jonathan completed multiple UROPs in Ikezu lab, graduated BU in 2014, and joins Dr. Greco lab at Department of Genetics and Dermatology, Yale University as a research technician.

IMG_1571Grant Yonemoto (BU Biology Major)
Updates: Received UROP research award for 2013 summer
 Co-authored in Am J Pathol. 2014 Mar;184(3):808-18Updates: Grant is currently working at Morgan Stanley in NY.