People

Principal Investigator

10-3009-PHARMAHEAD_Ikezu-116  

Tsuneya Ikezu, MD/PhD – Professor of Pharmacology and Neurology

 

Research Staff

Ikezu,SeikoSeiko Ikezu, MD – Senior Scientist
Research: Seiko’s research is focused on genetic and pharmacological modulation of protein kinases, namely tau-tubulin kinases(TTBK), which are  involved in aggregation of neuropathogenic protein, such as microtubule-associated protein tau, alpha-synuclein, and TDP-43.  Phosphorylation of the amyloidgenic proteins are found in the Ubiquitin-positive inclusion bodies of Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease and amyotrophic lateral sclerosis. TTBK1 and 2 are potential therapeutic target of the proteinopathy-related neurodegeneration.
DSC_5178 Hirohide AsaiHirohide Asai, MD/PhD, Postdoctoral Fellow
Research: Hiro is studying the molecular mechanism of axonal degeneration and tauopathy development in transgenic mouse models of Alzheimer’s disease.
DSC_5183 Rob FreilichRobert W. Freilich (MD/PhD student)
Research: Rob’s research is aimed at understanding how microRNAs influence the neuroimmune response in the CNS, focused specifically on microglia and on identifying therapeutic that modulate the neurotoxic effects of microglia in Alzheimer’s Disease.
DSC_5184 Megan VarnumMegan Varnum (PhD student)
Research: Megan’s research focuses on the role of CD200 in Alzheimer’s disease.
maya_woodbury_portraitMaya Woodbury (PhD student, Graduate Program for Neuroscience/Program in Biomolecular Pharmacology)
Research: Maya is studying the molecular characterization of growth factors and glia-derived cytokines and their effect on neuroregeneration.

Alumni

Ingraham, KatieKaitlin Ingraham, BA Kaitlin was accepted into the UCLA Graduate ACCESS Program.