Principal Investigator

DSC_0015Neil J. Ganem, Ph.D.

Assistant Professor of Pharmacology and Medicine, Division of Hematology and Medical Oncology, Department of Pharmacology & Experimental Therapeutics




Graduate Students


Amanda Bolgioni, Graduate Student in Pharmacology

Amanda is a second year graduate student in the Department of Pharmacology and Experimental Therapeutics at Boston University. She joined the Ganem lab in May 2014. Amanda completed her undergraduate degree in Biochemistry at the University of Vermont (UVM) in 2013. Her undergraduate research at UVM focused on the importance of serotonin for gastrointestinal function, specifically how this neurotransmitter contributes to inflammatory bowel disease and irritable bowel syndrome when its regulation is altered.  Amanda’s research in the Ganem Lab is aimed at understanding the role of the Hippo pathway in regulating the “mitotic clock.”



Sanghee Lim PhotoSanghee Lim, Graduate Student in Pharmacology

Sanghee Lim is an MD/PhD student in the Department of Pharmacology and Experimental Therapeutics. He joined Dr. Ganem’s lab in the summer of 2014 following the completion of his pre-clinical studies at the BU School of Medicine. Sanghee graduated from the College of Arts and Sciences at Boston University through the Seven-Year Medical Education program with a degree in Medical Science and a degree with Honors in Political Science. As an undergraduate at BU, Sanghee worked with Dr. Herbert Cohen in the Renal Section at Boston Medical Center, investigating the relationship between Jade-1 (Gene for Apoptosis and Differentiation in Epithelia-1) and invasive phenotypes in models of renal cell carcinoma. Sanghee’s current work in the Ganem lab focuses on how oncogenic BRAF signaling contributes to genomic instability and disease progression in melanoma through extra-canonical pathways.

Lab Members




Allison Matthews, Research Technician

Allison Matthews is a research technician in the pharmacology department at Boston University. She joined the lab in July 2013 after completing her undergraduate degree in biochemistry at Mount Holyoke College in 2013. At Mount Holyoke she completed a thesis with Professor Amy Camp on the effect of a small inverted repeat sequence in the sigmaG promoter on Bacillus subtilis sporulation. Allison previously worked at MD Anderson Cancer Research Center on STAT3 signaling as well as at Brandeis University in the Haber lab studying the effects of CDC5 overexpression on DNA damage repair.

Hatim[1]Hatim Mustaly, Masters Student in Medical Sciences

Hatim Mustaly is a second year graduate student pursuing a Masters in Medical Sciences at Boston University School of Medicine, Division of Graduate Medical Sciences. Hatim completed his undergraduate degree in Neuroscience at Knox College in 2013. At Knox, his research focused on the mechanism of ventral nerve cord regeneration in Themiste lageniformis (Peanut worms). Hatim is currently testing potential small molecule modulators of LATS kinases.



photoTenny Mudianto, Undergraduate Student

Tenny Mudianto is an undergraduate student at Boston University, majoring in cell and molecular biology.  As she enters her third year in college, she has developed an interest in studying cancer cell biology and the cell cycle. Tenny joined Dr. Ganem’s lab in the Fall of 2014 and is examining how cancer cells overcome activation of the hippo tumor suppressor pathway. After graduating, she plans to pursue graduate study in biochemistry.

Lab Alumni

Elizabeth Shenk, Ph.D., 

Position: Staff Scientist at Alliance Pharmaceuticals, Boston, MA