Publications

Selected Peer-Reviewed Publications

Blasio A, Iemolo A, Sabino V, Petrosino S, Steardo L, Rice KC, Orlando P, Iannotti FA, Di Marzo V, Zorrilla EP, Cottone P. Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala. Neuropsychopharmacol. In Press.

Blasio A, Iemolo A, Sabino V, Petrosino S, Steardo L, Rice KC, Orlando P, Arturo Iannotti F, Di Marzo V, Zorrilla EP, Cottone P. Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdale. Neuropsycholpharmacology. 2013 Jun 24. Epub ahead of print.

Sabino V, Narayan AR, Zeric T, Steardo L, Cottone P. mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats. Behav Brain Res. 2013 Jun 15;247:9-16. PubMed PMID: 23466691; PubMed Central PMCID: PMC3646912.

Iemolo A, Blasio A, St Cyr SA, Jiang F, Rice KC, Sabino V, Cottone P. CRF-CRF1 Receptor System in the Central And Basolateral Nuclei Of The Amygdala Differentially Mediates Excessive Eating Of Palatable Food. Neuropsychopharmacology. 2013 Jun 10;PubMed PMID: 23748225.

Dore R, Iemolo A, Smith KL, Wang X, Cottone P, Sabino V. CRF Mediates the Anxiogenic and Anti-Rewarding, But Not the Anorectic Effects of PACAP. Neuropsychopharmacology.2013 May 9;PubMed PMID: 23657440.

Dore R, Valenza M, Wang X, Rice KC, Sabino V, Cottone P. The inverse agonist of CB1 receptor SR141716 blocks compulsive eating of palatable food. Addict Biol. 2013 Apr 16;PubMed PMID: 23587012.

Sabino V, Kwak J, Rice KC, Cottone P. Pharmacological characterization of the 20% alcohol intermittent access model in sardinian alcohol-preferring rats: a model of binge-like drinking. Alcohol Clin Exp Res. 2013 Apr;37(4):635-43. PubMed PMID: 23126554; PubMed Central PMCID: PMC3567206.

Cottone P, Sabino V, Nagy TR, Coscina DV, Levin BE, Zorrilla EP. Centrally administered urocortin 2 decreases gorging on high-fat diet in both diet-induced obesity-prone and -resistant rats. Int J Obes (Lond). 2013 Mar 12;PubMed PMID: 23478425.

Cottone P, Iemolo A, Narayan AR, Kwak J, Momaney D, Sabino V. The uncompetitive NMDA receptor antagonists ketamine and memantine preferentially increase the choice for a small, immediate reward in low-impulsive rats. Psychopharmacology (Berl). 2013 Mar;226(1):127-38. PubMed PMID: 23104264; PubMed Central PMCID: PMC3572289.

Blasio A, Steardo L, Sabino V, Cottone P. Opioid system in the medial prefrontal cortex mediates binge-like eating. Addict Biol. 2013 Jan 24;PubMed PMID: 23346966; PubMed Central PMCID: PMC3664255.

Parylak SL, Cottone P, Sabino V, Rice KC, Zorrilla EP. Effects of CB1 and CRF1 receptor antagonists on binge-like eating in rats with limited access to a sweet fat diet: lack of withdrawal-like responses. Physiol Behav. 2012 Sep 10;107(2):231-42. PubMed PMID: 22776620.
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Iemolo A, Valenza M, Tozier L, Knapp CM, Kornetsky C, Steardo L, Sabino V, Cottone P. Withdrawal from chronic, intermittent access to a highly palatable food induces depressive-like behavior in compulsive eating rats. Behav Pharmacol. 2012 Sep;23(5-6):593-602. PubMed PMID: 22854309.

Cottone P, Wang X, Park JW, Valenza M, Blasio A, Kwak J, Iyer MR, Steardo L, Rice KC, Hayashi T, Sabino V. Antagonism of Sigma-1 Receptors Blocks Compulsive-Like Eating Neuropsychopharmacology. 2012 Nov; 37(12);2593-604 . .

Blasio A, Narayan AR, Kaminski BJ, Steardo L, Sabino V, Cottone P. A modified adjusting delay task to assess implusive choice between isocaloric reinforcers in non-deprived male rats: effects of 5-HT2A/C and 5-HT1A receptor agonists. Psychopharmacology (Berl). 2012 Jan; 219(2):377-86. .

Fekete EM, Zhao Y, Szücs A, Sabino V, Cottone P, Rivier J, Vale WW, Koob GF, Zorrilla EP. Systemic urocotrin 2, but not urocortin 1 or stressin 1-A, suppresses feeding via CRF2 receptors without malaise and stress. Br J Pharmacol. 2011 Dec; 164(8):1959-75. .

Sabino V, Cottone P, Blasio A, Iyer MR, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. Activation of σ-receptor induces binge-like drinking in Sardinian alcohol-preferring rats. Neuropsychopharmacology. 2011 May; 36(6):1207-18. PMC 3079320. .

Repunte-Canonigo V, Berton F., Cottone P, Reifel-Miller A, Roberts AJ, Morales M., Francesconi W, Sanna PP. A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake. Brain Res 2010 Jun 21; 1339:11-7. PMC2906226. .

Repunte-Canonigo V, van der Stap LD, Chen J, Sabino V, Wagner U, Zorrilla EP, Schumann G, Roberts AJ, Sanna PP. Genome-wide gene expression analysis identifies K-ras as a regulator of alcohol intake. Brain Res. 2010 Jun 21;1339: 1-10. PMC2925131..

Roberto M, Cruz MT, Gilpin NW, Sabino V, Schweitzer P, Bajo M, Cottone P, Madamba SG, Stouffer DF, Zorrilla EP, Koob GF, Siggins GF, Parson LH. Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release play a key role in alcohol dependence. Biol Psychiatry. 2010 May 1; 67(9):831-9. PMC2883449. .

Cottone P, Sabino V, Roberto M, Bajo M, Pockros L, Frihauf J, Fekete EM, Steardo L, Rice KC, Grigoriadis D, Conti B, Koob GF, Zorrilla EP. CRF system recruitment mediates dark side of compulsive eating. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):20016-20. PMC Journal 2785284
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The paper has been evaluated by the Faculty of 1000 Biology: 9, Excellent. Heilig, Markus .

Fonareva I, Spangler E, Cannella N, Sabino V, Cottone P, Ciccocioppo R, Zorrilla EP, Ryabinin AE. Increased perioculomotor Urocortin 1 immunoreactivity in genetically selected alcohol preferring rats. Alcohol Clin Exp Res. (2009); 33(11):1956-65. PMC 2813693..

Sabino V, Cottone P, Zhao Y, Steardo L, Koob GF, Zorrilla EP. Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist. Psychopharmacol 2009; 205(2): 327-335. PMC2748837

Greenwell TN, Funk CK, Cottone P, Richardson HN, Chen SA, Rice KC, Zorrilla EP, Koob GF. Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long-, but not short-access rats. Addiction Biology 2009 Apr;14(2):130-43. PMC2748834

Sabino V, Cottone P, Parylak SL, Steardo L, Zorrilla EP. Sigma-1 receptor knockout mice display a depressive-like phenotype. Behav Brain Res 2009; 198(2): 472-476. PMC2667953

Sabino V, Cottone P, Zhao Y, Iyer M, Steardo L yr, Steardo L, Rice KC, Conti B, Koob GF, Zorrilla EP. The sigma receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking. Neuropsychopharmacol 2009; 34(6): 1482-93. PMC2669694

Cottone P, Sabino V, Steardo L, Zorrilla EP. Consummatory, anxiety-related and metabolic adaptations in female rats with alternating access to preferred food. Psychoneuroendocrinol 2009; 34(1):38-49. PMCID: PMC3224792.

Greenwell TN, Walker BM, Cottone P, Zorrilla EP, Koob GF. The alpha(1) adrenergic receptor antagonist prazosin reduces heroin self-administration in rats with extended access to heroin administration. Pharmacol Biochem Behav. 2009; 91(3):295-302. PMC2637926

Cottone P, Sabino V, Steardo S, Zorrilla EP. Intermittent preferred food access reduces the reinforcing efficacy of chow in rats. Am J Physiol Regul Integr Comp Physiol 2008; 295(4):R1066-76. PMC2576087

Cottone P, Sabino V, Steardo L, Zorrilla EP. Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food. Neuropsychopharmacol 2008; 33(3):524-35. PMC Journal – In Process

George O, Ghozland S, Azar MR, Cottone P, Zorrilla EP, Parsons LH, O’Dell LE, Richardson HN, Koob GF. CRF-CRF1 system activation mediates withdrawal-induced anxiety-like behavior and increases in nicotine self-administration in nicotine dependent rats. Proc Natl Acad Sci 2007; 104(43):17198-203. PMC2040467

Cottone P, Sabino V, Nagy TR, Rivier JE, Coscina DV, Zorrilla EP. Feeding microstructure in diet-induced obesity susceptible and resistant rats: comparative central effects of urocortin 2. J Physiol 2007; 583(Pt 2):487-504. PMC2277029

Sabino V, Cottone P, Steardo L, Schmidhammer H, Zorrilla EP. 14-methoxymetopon, a highly potent mu opioid agonist, biphasically affects ethanol intake in Sardinian alcohol-preferring rats. Psychopharmacol 2007; 192(4):537-46. PMC Journal – In Process

Cottone P, Sabino V, Steardo L, Zorrilla EP. FG 7142 specifically reduces meal size and the rate and regularity of sustained feeding in female rats: evidence that benzodiazepine inverse agonists reduce food palatability. Neuropsychopharmacol 2007; 32(5):1069-81. PMC Journal – In Process

Sabino V, Cottone P, Koob GF, Steardo L, Lee MJ, Rice KC, Zorrilla EP. Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats. Psychopharmacol 2006; 189(2):175-86. PMC Journal – In Process

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