Laboratories of Training Faculty

 

All core Pharmacology laboratories, affiliated laboratories, and centers that provide opportunities for student laboratory rotation experiences and thesis research are listed below. (See the full list of program faculty here.)

Laboratory Name Description
Biomedical Microdevices and Microenvironments The lab is focused on the design and engineering of manufacturable, disposable microfluidic systems for low-cost point-of-care molecular diagnostics.
Biomedical Optics Lab The development of minimally-invasive diagnostic and therapeutic tools based on optical technologies.
Biomimetic Materials Engineering Laboratory Aims to understand how bioscaffold properties (e.g. structural, mechanical, and chemical) affect vascular smooth muscle cells’ migration and growth
Biomolecular Systems Laboratory Develops and applies computational/mathematical methods, and high throughput experimental methods, to analyze changes in gene and protein expression profiles of cells in response to various endogenous and exogenous signals.
The Grinstaff Group Pursues highly interdisciplinary research in the areas of biomedical engineering and macromolecular chemistry.
Hasselmo Laboratory Understanding neuromodulation and cortical function, using a combination of neurophysiological and behavioral experiments along with computational modeling.
Laboratory of Addictive Disorders Research focused on expanding our understanding of the pathophysiology and prevention of psychiatric diseases, and apply this to the development of novel therapeutics.
Laboratory of Addiction Genetics Using forward and reverse genetic approaches in mice to accelerate our understanding of the neurobiological mechanisms of complex traits associated with substance abuse and applying these findings toward preventative and treatment strategies in humans.
Laboratory of Behavioral Neuroscience Research focuses on elucidating the causes and developing treatments for drug addiction using animal models. The Laboratory of Behavioral Neuroscience has operant chambers for rats and mice to study drug self-administration, drug discrimination and schedule-controlled behavior.
Laboratory of Behavioral Pharmacology Researches the interaction between the brain’s pain and reward systems.
Laboratory of Cancer Cell Biology Dr. Ganem’s lab seeks to define the tumor suppression mechanisms that  limit the proliferation of highly abnormal aneuploid cells, as well as to identify the common genetic adaptations made by cancer cells to overcome these growth barriers.
Laboratory of Cancer Pharmacogenomics Studies global mechanisms underlying oncogene-driven cancer progression.
Laboratory for Cardiovascular-Renal Research Laboratory focuses on the central neural control of fluid and electrolyte homeostasis and blood pressure regulation
Laboratory of Carmela Abraham Researches Alzheimer’s Disease and normal aging of the brain.
Laboratory of Cellular Neurobiology Interested in the electrophysiological and morphological properties of neocortical neurons in the rodent and primate prefrontal cortex across the lifespan.
Laboratory of Cognitive Neurobiology To enhance knowledge about hippocampal function, they are pursuing a combination of neuropsychological studies of the nature of memory loss in animals with damage to the hippocampus and related cortical areas, and pursuing electrophysiological recording studies.
Laboratory of Diabetes and Obesity Research Interested in understanding the insulin signaling transduction and cellular mechanisms of diabetes and inmate immunity and early stage inflammation involved in obesity and related complications.
Laboratory of Gary B. Kaplan Utilizes state-of-the-art methods in behavioral neuroscience, neuroanatomy, and neurochemistry to study these signaling pathways and circuitry in addiction.
Laboratory of Genome Instability and Cancer Therapeutics

Research focuses on understanding how telomere dysfunction contributes to the development of cancer

Laboratory of Hengye Man Glutamate receptor expression, trafficking and turnover in synaptic plasticity.
Laboratory of Molecular Neurobiology Involved in basic research on receptor pharmacology and the mechanisms by which receptors are regulated. Lab activities are divided into Molecular Biology, Electrophysiology, and Tissue Culture and Cell Biology.
Laboratory of Molecular Psychiatry in Aging Use our research findings to develop diagnostic tools and effective treatments for AD and other diseases in geriatric psychiatry.
Laboratory of Molecular NeuroTherapeutics Focuses on neuroimmune cell-mediated regulations of neuronal function, neurogenesis, neuroinflammation, and neurodegeneration.
Laboratory of Neurodegeneration Currently identifying which of the pathways modulate the neurodegenerative pathways associated with Parkinson’s disease.
Laboratory of Translational Epilepsy (LTE) Interested in deciphering the complex networks of gene regulation that control the function of inhibitory neurotransmission in the brain and harnessing them to develop treatments for epilepsy and other related neurological disorders.
Laboratory of Zebrafish Genetics & Cancer Therapeutics Research interests focus on identifying novel genes and pathways that are essential for MYC-related tumor transformation and progression, particularly for T-Lymphoblastic Lymphoma/Leukemia.
The Molecular Neuropharmacology Laboratory The research primarily focuses on adenosine, a naturally occurring nucleoside which exists ubiquitously throughout the body as a cellular metabolic intermediary and also functions as a neuromodulator in brain.
Neuroengineering Lab Invents and applies a variety of genetic, molecular, pharmacological, optical, and electrical tools to correct neural circuits that go awry within the brain.
Walsh Laboratory Investigates the signaling- and transcriptional-regulatory mechanisms that control both normal and pathological tissue growth in the cardiovascular system, the role of the immune system in vascular disease, and the actions of adiponectin on cardiovascular tissues.
Whitaker Cardiovascular Institute Established in 1974 to foster advances in research, treatment, and education in the broad area of heart and vascular disease.