Carol T. Walsh, Ph.D.

CAROL T. WALSH, Ph.D.

Professor of Pharmacology
Department of Pharmacology

Ph.D., Boston University

Curriculum Vitae

Research Interests

Pharmacokinetics

Research interests include gastrointestinal pharmacology, the toxicology of metal compounds, and pharmacokinetics. Projects have included the elucidation of the hypocholesterolemic effect of pharmacologic agents, evaluation of the gastrointestinal toxicity of lead, and a critical review of the toxicology of zinc. Pharmacokinetic studies have included work with opiate analgesics, phenothiazines, pyrimidine and purine analogue anticancer agents, antiepileptic agents, mercury-containing compounds, and butyric acid derivatives for sickle cell anemia and thalessemias.

Selected Publications

C.T. Walsh and R.D. Schwartz-Bloom (2005). Levine’s Pharmacology: Drug Actions and Reactions. Seventh Edition, Taylor & Francis, Inc.

Walsh, C.T. (2001) Methods in Gastrointestinal Toxicology. In: Methods in Toxicology, A.W. Hayes, ed., 4th edition, Raven Press, pp. 1215-1240.

Walsh, C.T. (1997) Toxicokinetics: Oral exposure and absorption of toxicants. In: I.G. Sipes et al., eds. Comprehensive Toxicology, Elsevier Science, LTD, Vol. 1, Ch 3, pp. 51-61.

Walsh, C.T. and M.C. Neville (1994) Effects of xenobiotics on milk secretion and composition. J. Nutr. Biochem., 5:418-441.

Perrine, S.P., G. Dover, P. Daftari, C.T. Walsh, Y. Jin, A. Mays and D.V. Faller (1994) Isobutyramide, an orally bioavailable butyrate analogue, stimulates fetal globin gene expression in vitro and in vivo. British J. of Haematology, 88:555-561.

Walsh, C.T., H.H. Sandstead, A.S. Prasad, P.M. Newberne and P.J. Fraker (1994) Zinc: Health effects and research priorities for the 1990s. Environmental Health Perspectives, 102(Suppl 2):5-46.

Browne, T.R., G.K. Szabo, C.T. Walsh, G.E. Schumacher, J.E. Evans and B.A. Evans (1990) New Pharmacokinetic Methods II. Determination of the Presence or Absence of Product Inhibition in Drugs with Nonlinear Pharmacokinetics. J. Clin. Pharmacol. 30:578-584.

Harnett, K.M., C.T. Walsh and L. Zhang (1989) Effects of Bay o 2752, a Hypocholesterolemic Agent, on Intestinal Taurocholate Absorption and Cholesterol Esterification. J. Pharmacol. Exp. Ther. 251:502-509.

Contact

Office: R-610
Phone: 617-638-4326
Fax: 617-638-4329