Martin H. Kroll, MD

Professor
Chief, Laboratory Medicine

Degrees

University of Maryland, College Park, MD BS Chemistry
University of Maryland School of Medicine, Baltimore, MD MD Medicine
University of Maryland Hospital, Baltimore, MD Resident Anatomic and Clinical Pathology
National Institutes of Health, Bethesda, MD Fellowship Clinical Pathology

Employment

  • October 2007 to Present, Chief, Department of Laboratory Medicine, Boston Medical Center, H3600, 88 East Newton Street, Boston, MA  02118.
  • September 2005 to December 2007: Professor of Pathology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, Texas  75235.
  • June 2004 to December 2007: Director of Core Laboratories, Veterans Affairs North Texas Health Care System, Dallas VA Medical Center, 4500 Lancaster Rd., 113, Dallas, Texas  75216.
  • December 1999 to present:  Director of Clinical Chemistry, Veterans Affairs North Texas Health Care System, Dallas VA Medical Center, 4500 Lancaster Rd., 113, Dallas, Texas  75216.
  • December 1999 to present:  Associate Professor, Pathology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, Texas  75235.
  • January 1994 to December 1999:  Associate Professor, Department of Pathology, The Johns Hopkins School of Medicine, 600 N. Wolfe St., Meyer B-125, Baltimore, Maryland  21287-7065.
  • January 1994  to December 1999:  Associate Director, Clinical Chemistry Division, Department of Pathology, The Johns Hopkins Hospital, 600 N. Wolfe St., Meyer B-125, Baltimore, Maryland  21287-7065.
    October  1994  to January 1997:  Director, Central Services Division, Department of Pathology, The Johns Hopkins Hospital, 600 N. Wolfe St., Meyer B-125, Baltimore, Maryland  21287-7065.
  • July 1, 1994 to October 1996.  Director, Johns Hopkins at Green Spring Station, The Johns Hopkins Suburban Health Center Limited Partnership, Department of Pathology, The Johns Hopkins Medical Institutions, Laboratory and Radiology, 10755 Falls Road, Suite 150, Lutherville, Maryland  21093
  • August 1984 to January 1994  Medical Staff Officer, Senior Staff in charge of the General  Chemistry Group, Clinical Chemistry Service, Clinical Pathology Department,  Clinical Center, National Institutes of Health, Building 10, Room 2C-407,  Bethesda, Maryland,  20892.

Research Interests

I perform research in many different areas of Clinical Chemistry and Laboratory Medicine.  Pertinent areas of investigation include clinical trials of LDL subfractionation.  Further, I am interested in developing solutions based on statistical methodologies, especially as they involve test interpretation.

My major areas of research interest pertain to the development of mathematical models and of physiologic and pathologic systems.  I employ the application of dynamic system theory, using such tools as differential and nonlinear equations.  Under current study are
blood coagulation, biological variation, and vasomotion in the microcirculation using laser Doppler flow.

Recent Publications

  • Choi T-S, Khan A, Greilich PE, Kroll MH.  Modified plasma-based ecarin clotting time assay for monitoring of recombinant hirudin during cardiac surgery.  Amer J Clin Pathol, 2006;125:290-5.
  • Khan AI, Vasquez Y, Gray J, Wians Jr FH, Kroll MH.  The variability of results between point-of-care testing glucometers and the central laboratory analyzer.  Arch Path Lab Med, 2006;130:1527-1532.
  • Srisawasdi P, Jearanaikoon P, Wetprasit N, Sriwanthana B, Kroll MH, Loleha PH.  Application of Streptomyces and Brevibacterium cholesterol oxidase for total serum cholesterol assay by the enzymatic kinetic method.  Clin Chim Acta.  2006;372:103-111.
  • Kroll MH, Srisawasdi P.  BioSystems.  The clearance of BNP modeled using the NT-proBNP—BNP relationship.  (2006;May 26, Epub.) 2007;88:147-155.
  • Srisawasdi P, Kroll MH, Lolekha PH.  Advantages and disadvantages of serum cholesterol determination by the kinetic versus the endpoint method.  Amer J Clin Path.  2007; 127:906-918.
  • Kroll MH, Twomey PJ, Srisawasdi P.  Using the single-compartment ratio model to calculate half-life, NT-proBNP as an example. Clinica Chimica Acta.  2007. May;380:197-202; EPub 2007 Feb. 23.
  • Srisawasdi P, Chaichanajarernkul U, Teerakranjana N, Kroll MH.  Implementation of Cellulomonas cholesterol oxidase for total serum cholesterol determination by endpoint method.  J Clin Lab Analysis, in press (2007).
  • Twomey P, Kroll MH. How to use linear regression and correlation in quantitative method comparison studies.  International J Clin Practice. In press (2008).
Primary teaching affiliate
of BU School of Medicine