Pathology & Laboratory Medicine News Items – December 2016/January 2017

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February 1st, 2017

Pathology & Laboratory Medicine News Items – December 2016/January 2017

  • Announcements:
      • The Pathology Residency and Cytopathology Fellowship Programs, are proud to announce the ACGME’s decision for the Continued Accreditation for both programs.  Congratulations and thanks to everyone for a job well done!
            •  Rahimi.Cover.2016
        • Dr. Grace Zhao reported; “Congratulations, your Mallory Project is approved with a total budget of $6925. The approved budget is over the budget cap of $5000 because of the potential to expand the IHC list of stains within the Department”
        • Dr. Deborah Stearns-Kurosawa was invited to be a member of the scientific steering committee for the 10th International Symposium on Shiga Toxin (Verocytotoxin) Producing E.coli Infections (VTEC 2018) to be held in Florence, Italy in May 2018
        • Dr. Carmen Sarita-Reyes’s Mallory Proposal has been approved. The Department has provided funds for two medical students to participate in the 8 summer fellowship through the Mallory funds
        • Dr. Barbara Nikolajczyk presented at the following:
          • Endocrinology Grand Rounds, Boston University School of Medicine, Defining Inflammation in Human Obesity and Type 2 Diabetes, November 14 2016
          • Endocrinology Grand Rounds, University of Massachusetts School of Medicine, Defining Inflammation in Human Obesity and Type 2 Diabetes, December 13, 2016
        • Dr. Daniel  Remick presented in December:
          • Grand Rounds Speaker, Yale School of Medicine, Department of Pathology, “Traumatic Brain Injury Augments Host Defenses”
          • Grand Rounds Speaker, Boston Medical Center, Department of Internal Medicine, “Sepsis: A Moving Target”
        • Dr. Daniel Remick in January:
          • The Houston Methodist Hospital held their first Annual Pathology Research Day on Saturday, January 14th. First year pathology residents presented posters and the upper year residents and fellows each gave 5-7 minute presentation on their projects. Dr. Remick was the Keynote Speaker and gave the talk “Mild Traumatic Brain Injury Augments Innate Immunity”
        • Jason Sutin, PhD (Off-Site at MGH Franceschini Lab) successfully defended his Thesis, “Development of a Novel Diffuse Correlation Spectroscopy Platform for Neuromonitoring Cerebal Blood Flow and Oxygen Metabolism: From Novel Concepts and Devices to Preclinical Live Animal Studies” Fall 2016, BRAVO!!
        • Barbara Nikolajczyk, PhD received a $20,000.00 grant titled “Inflammation in type 1 diabetes” from Boston University CTSI
        • Dr. Nikolajczyk will also be a reviewer on two NIH panels in Feb:
          • Cellular Aspects of Diabetes and Obesity Study Section, Ad-hoc (2017)
          • NIDDK Fellowship and Conflict Study Section, Ad-hoc (2017)
          • New People:
            • The Nikolajczyk Lab has added Joseph Lee, Masters in Nutrition student
      • Publications ACCEPTED:
        • Mahmoud L Soliman, MD PhD, Ashish Tiwari, MD, Grace Zhao MD, PhD “Coexisting tubular adenoma with a high-grade neuroendocrine carcinoma of colon allowing early surgical intervention and implicating a shared stem cell origin.” The World Journal of Gastroenterology
        • Li C, Wang D, Lv X, Jing R, Bi B, Chen X, Guo J, Wang F, Sun S, Azadzoi KM, Yang JH: Yersinia pestis acetyltransferase-mediated dual acetylation at the serine and lysine residues enhances the auto-ubiquitination of ubiquitin ligase MARCH8 in human cells. Cell Cycle (accepted for publication)
        • Nicholas DA, Proctor EA, Raval FM, Ip BC, Habib C, Ritou E, Grammatopoulos TN, Steenkamp D, Dooms H, Apovian CM, Lauffenburger DA and Nikolajczyk BS. 2017. Advances in the Quantification of Mitochondrial Function in Primary Human Immune Cells through Extracellular Flux Analysis (Accepted, PLOS ONE)
      • Publications PUBLISHED:
      • The Department’s strategic plan included increasing our academic stature. To achieve this the guidelines for Mallory Research Projects were sent to the faculty. There was an excellent response and the following Mallory proposals were funded in the Fall of 2016.
        1. Cell cycle regulator JADE1 protein: a novel marker of colon cancer in humans
          1. Drs. Panchenko, O’Brien and Tan
        2. Defining gene programs regulated by Ikaros in T cells
          1. Drs. Winandy and Lee
        3. Validation of Maspin/VHL immunostain for distinguishing carcinoma from reactive atypia in pancreas
          1. Drs. Tan, Yang, and Zha
        4. Local Release of Substance P after mild traumatic brain injury primes the host to survive a subsequent pathogen challenge
          • Drs. Remick and Kim