Departmental Seminar – Friday November 6
November 6 – Friday @ 2:00
“The Role of Viral Protein R in HIV-1 Infection”
Caitlin Miller, PhD Candidate
Department of Pathology, Gummuluru Lab
Boston University School of Medicine
Refreshments at 1:45 p.m.
670 Albany Street – Lobby Level #107/108
Contact:
Program Director, Barbara Slack, PhD
Program Coordinator: Debra Kiley, 414-7914
Target Audience: Faculty, Students, Residents, Greater Boston Scientific Community (advertised in MIT’s Bulletin).
At the conclusion of this activity participants will be able to: 1) state that better understanding of the science behind therapeutic research and development will help physicians be able to treat patients more safely and effectively in the future; 2) discuss that the HIV auxiliary protein Vpr potently blocks the cell cycle at the G2/M transition and 3) recall that G2/M arrest results from untimely activation of the structure-specific endonuclease (SSE) regulator SLX4 complex (SLX4com) by Vpr, a process that requires VPRBP-DDB1-CUL4 E3-ligase complex.