December 2014

Pathology & Laboratory Medicine News Items

 Announcements:

  • Nader Rahimi, PhD was awarded a R21 grant from NIH/NCI entitled “Overcoming the resistance to anti-angiogenesis therapy”. The overall of goal of this research is to study the role of posttranslational modifications on VEGFR-2 in colon cancer. Angiogenesis inhibitors targeting the VEGF signaling pathway have been FDA approved for various cancer treatments. Although beneficial, patients inevitably develop resistance and often fail to demonstrate significantly better overall survival. Interfering with the posttranslational modifications of VEGFR-2 may overcome refractoriness and resistance to certain class of anti- cancer drugs.
  • Dr. Daniel Remick was an invited speaker to Loyola University Medical Center in Chicago, December 9/10, 2014:
    • Dr. Remick presented Grand Rounds in the Department of Surgery at Loyola – “Brain Injury Prevents Pneumonia – Who knew?”
    • He also gave a lecture to the Department of Pathology “Physician Scientist Pathway in Pathology”
    • Dr. Remick, as an invited speaker at the Burn and Shock Trauma Research Institute at Loyola University – Chicago presented,  “Inhibitory IgG Increases Sepsis Mortality”
  • Dr. Chris Andry, of Boston University USA, visited Professor Rodger Charlton, and other colleagues in the Division of Primary Care, Nottingham University, United Kingdom on 9th December, 2014 . During his visit, Dr. Andry gave a talk entitled “The Value of a Centralized Hospital Bereavement Office Supporting Multicultural Families in the USA”   

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    UK meeting University of Nottingham. Dr. Andry, 2nd from left. Man on his right Professor Rodger Charlton. Man on his left Dean of Srinakharinwirot University, Thailand. First Woman to the right of Professor Charlton, Assistant Professor Nantana Choomchuay, MD. Head, Department of Pathology, Faculty of Medicine, Srinakharinwirot University.
  • Jenny McEldoon, BU Undergrad working in the Remick Lab has been awarded funding from UROP for Spring 2015!
  • Zachary Hunter, PhD, Steve Treon Lab at Children’s Hospital, successfully defended his thesis “Whole Genome Sequencing Reveals that Recurrent MYD88 and CXCR4 Mutations Underlie the Genomic Landscape of Waldenström’s Macroglobulinemia” on Tuesday, December 2nd

Publications ACCEPTED:

  • Inge The, Suzan Ruijtenberg, Benjamin Bouchet, Alba Cristobal, Martine B.W. Prinsen, Tim van Mourik, John Koreth, Huihong Xu, Albert J.R. Heck, Anna Akhmanova, Edwin Cuppen, Mike Boxem, Javier Munoz, and Sander van den Heuvel, Rb and the APC/C co-activator FZR1 determine CDK4/6-Cyclin D requirement in C. elegans and human cancer cells. Nature Communications
  • Akifumi Fujita, Huihong Xu, Yu-Ming Chang, Scharukh Jalisi, and Osamu Sakai, Best cases from the AIRP: Malignant mixed tumor of the hard plate. RadioGraphics
  • Authors: Blanche C. Ip, Andrew E. Hogan, Barbara S. Nikolajczyk; Lymphocyte roles in metabolic dysfunction: of men and mice  Trends in Endocrinology and Metabolism  
  • Michael J. Greene, Elena S. Klimtchuk, David C. Seldin, John L. Berk, and Lawreen H. Connors; “Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal” Biochemistry

Publications: PUBLISHED:

  • Stevenson EK, Sloan KA, Narsule CK, Kretschman DM, Sarita-Reyes CD, Steiling K, Ebright MI. Catamenial hemothorax in a patient with multiple sclerosis. Am J Respir Crit Care Med. 2014 Dec 15; 190(12):e69-70
  • Zhang QSiroky M, Yang JH, Zhao Z and Azadzoi K “Effects of ischemia and oxidative stress on bladder purinoceptors expression” Urology, 2014 Nov;84(5):1249.e1-7. doi: 10.1016/j.urology.2014.07.023