Ruiyi (Flora) Ren
Staff
Department of Biochemistry
Amyloid Research Program
Boston University School of Medicine
80 E. Concord Street, L904
Boston, MA 02118
Lab Phone: 617-638-4536
Fax: 617-638-3997
Email: ruiyi@yahoo.com
Education
MS in Forensics
MS in Biochemistry
Research Interests
I took advantage of the ability to take courses while working and as I was interested in Forensics I was able to get my Masters while working. My other interests are in Amyloid and I am part of the Amyloid research program. In my research I use atomic force microscopy to examine oligomerization and fibril formation of Amyloid proteins in association with glycosaminoglycans. The reason is that these sugar chains are often found associated with the fibrils in the diseased tissue. I also help on a collaborative project between Harvard and Northeastern University that is developing a synthetic cornea.
Publications
Monis, G, Schultz C, Ren R, Eberhard J, Costello E.C, Connors L, Skinner,M and Trinkaus-Randall,V. Role of endocytic inhibitory drugs on internalization of amyloidogenic light chains by cardiac fibroblasts. Amer J Pathol. 169 (6) 1939-52, 2006
Ren R, Hutcheon AEK, Guo XQ, Melotti S, Ruberti JW, Zieske JD and V. Trinkaus-Randall. Human primary corneal fibroblasts synthesize and deposit proteoglycans in longterm 3_D cultures. Dev Dyn. 237L2705-2715. 2008.
Mayo C, Ren R, Rich C, Stepp MA and V. Trinkaus-Randall, Regulation by P2X7: Epithelial migration and stromal organization in the cornea. Inv Ophthal Vis Sci. 49: 4384-4391. 2008.

