Ruiyi (Flora) Ren

renStaff
Department of Biochemistry

Trinkaus-Randall Lab

Amyloid Research Program

Boston University School of Medicine
80 E. Concord Street, L904
Boston, MA 02118

Lab Phone: 617-638-4536

Fax: 617-638-3997

Email: ruiyi@yahoo.com

Education

MS in Forensics
MS in Biochemistry

Research Interests

I took advantage of the ability to take courses while working and as I was interested in Forensics I was able to get my Masters while working.  My other interests are in Amyloid and I am part of the Amyloid research program. In my research I use atomic force microscopy to examine oligomerization and fibril formation of Amyloid proteins in association with glycosaminoglycans. The reason is that these sugar chains are often found associated with the fibrils in the diseased tissue.  I also help on a collaborative project between Harvard and Northeastern University that is developing a synthetic cornea.

Publications

Monis, G, Schultz C, Ren R, Eberhard J, Costello E.C, Connors L, Skinner,M and Trinkaus-Randall,V. Role of endocytic inhibitory drugs on internalization of amyloidogenic light chains by cardiac fibroblasts. Amer J Pathol. 169 (6) 1939-52, 2006

Ren R, Hutcheon AEK, Guo XQ, Melotti S, Ruberti JW, Zieske JD and V. Trinkaus-Randall. Human primary corneal fibroblasts synthesize and deposit proteoglycans in longterm 3_D cultures. Dev Dyn. 237L2705-2715. 2008.

Mayo C, Ren R, Rich C, Stepp MA and V. Trinkaus-Randall, Regulation by P2X7: Epithelial migration and stromal organization in the cornea. Inv Ophthal Vis Sci. 49: 4384-4391. 2008.

Primary teaching affiliate
of BU School of Medicine