Partha Chakrabarti
Postdoctoral Fellow
Department of Biochemistry
Boston University School of Medicine
Silvio Conte Building, K110
72 E. Concord Street
Boston, MA 02118
Lab Phone: 617-638-5068
Fax: 617-638-5339
Email: partha@bu.edu
Education
MBBS, University of Calcutta, India
MD, Banaras Hindu University, India
PhD, Boston University School of Medicine
Research Interests
To understand the complexities in the signaling outputs from the energy and nutrient sensors such as AMP-activated protein kinase (AMPK), mammalian target of rapamycin complex 1 (mTORC1), sirtuins, forkhead O (FoxO) transcription factors etc in the context of adipocyte biology. Specifically, I am studying molecular mechanisms of lipolysis and in particular, transcriptional regulation of rate-limiting lipolytic gene Adipose Triglyceride Lipase (ATGL).
Publications
Partha Chakrabarti and Konstantin V. Kandror. (2009) FoxO1 controls insulin-dependent ATGL expression and lipolysis in Adipocytes. Accelerated publications J. Biol. Chem. (In press)
Partha Chakrabarti, Takatoshi Anno, Brendan Manning, Zhijun Luo and Konstantin V. Kandror. (2008) The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5′-untranslated region in the expression of leptin messenger ribonucleic acid. Mol. Endocrinol. 22: 2260-67
Ramkrishna Gupta, Partha Chakrabarti, Madhu Dikshit and Debabrata Dash. (2007) Late signaling in the activated platelets upregulates tyrosine phosphatase SHP1 and impairs platelet adhesive functions: Regulation by calcium and Src kinase. Biochim. Biophys. Acta, 1773: 131-40
Partha Chakrabarti, Bimal K. Panda and Debabrata Dash. (2006) Detection of Gγ(Aγδβ)0 thalassemia in North India. Clin Chim Acta, 364: 363-4.
Partha Chakrabarti, Ramkrishna Gupta, Asutosh Misra, Madhukar Rai, Vijay Pratap Singh and Debabrata Dash. (2005) Spectrum of β-thalassemia mutations in North-Indian states: a β-thalassemia trait with two mutations in cis. Clin Biochem, 38: 576-578
Partha Chakrabarti, Zubair Ahmad Karim, Ramkrishna Gupta, Vinita Wadhawan, Saikat Mukhopadhyay and Debabrata Dash. (2004) Biochemical characterization of Glanzmann’s Thrombasthenia, a rare genetic disorder affecting platelet function. Ind. J. Med. Biochem. 8: 56-60
