Erin M. Smith
Graduate Student
Department of Biochemistry
Symes Laboratory
Boston University School of Medicine
Silvio Conte Building, K409
72 E. Concord Street
Boston, MA 02118
Lab Phone: 617-638-4181
Fax: 617-638-5339
Email: ensmith@bu.edu
Education
B.S. Northeastern University, Boston MA
Research Interests
I am a graduate student in the laboratory of Dr. Karen Symes where we are investigating the mechanisms of cell movement. To do this I am using the frog, Xenopus laevis as my model system. My project title is “The role of PDGF-A in the driected migration of the mesendoderm during gastrulation”. Currently I am examining what role fibronectin and heparan sulfate proteoglycans may play in this directed cell movement. Our lab employs several different and exciting methodologies including using Real-Time PCR, ex vivo migration assays, microdissections, mRNA microinjections, subcloing, and microscopy.
Publications
Sengupta, S., Smith, E.M., Kim, K., Murnane, M. J., and Smith, B.D. DNA hypermethylation near the transcription start site of collagen alpha2(I) gene (COL1A2) occurs in both cancer cell lines and primary colorectal cancers. Cancer Research. 63:1789-1797, 2003
