| Investigator |
Project Dates |
Title of Pilot and Feasibility Project
|
| Stuart Chipkin |
1992-1993 |
Obesity and insulin resistance in adipose |
| Nawfal Istfan |
1992-1993 |
Nutrient partitioning and insulin resistance in obesity |
| Kathleen Kelly |
1992-1994 |
Signal transduction in adipocytes |
| Donald Miller |
1992-1994 |
Long term health impact of body weight change |
| Aviva Must |
1992-1993 |
Jump start: a program to prevent obesity in low income children and families |
| Susan Roberts |
1992-1994 |
Dietary fat-genotype interactions in energy balance |
| Van Cherington |
1993-1995 |
Non-receptor tyrosine kinase activity during adipose differentiation |
| Bradford Lowell |
1993-1995 |
Targeted disruption of the Beta3-andrenergic receptor gene |
| Avron Spiro III |
1993-1995 |
Health effects of weight changes in adult males |
| Karen Strehlow |
1993-1994 |
Sympathetic function in obesity |
| Vildan Civelek |
1994-1996 |
Mechanism of intracellular pH change as indicator of early postreceptor insulin signaling |
| Kathleen Cook |
1994-1996 |
Developmental and physiological mechanisms for regulation of mRNA stability in adipocytes |
| Robert Frederich |
1994-1996 |
Initial characterization, physiology and pathology of the ob/ob gene product |
| Andrew Greenberg |
1994-1996 |
Molecular and nutritional regulation of the perilipins |
| Eleftheria Maratos-Flier |
1994-1996 |
Identification of novel hypothalamic genes that are differentially regulated in rodent obesity |
| Jacqueline Stephens |
1994-1995 |
The identification of cytosolic kinases involved in the signal transduction of TNF-induced insulin resistance in murine adipocytes |
| Steven Grinspoon |
1995-1997 |
Physiologic effects of IGF-1 in anorexia nervosa |
| James Hamilton |
1995-1997 |
Fatty acid incorporation into adipocytes: nuclear magnetic resonance studies |
| Konstantin Kandror |
1995-1997 |
GLUT4-containing vesicles: new proteins-new functions? |
| James Kirkland |
1995-1997 |
Effects of aging on rat preadipocyte function |
| Vedrana Susulic |
1995-1996 |
Identification of nutritionally responsive cis-regulatory elements within the obese gene |
| Jesse C. Chow |
1996-1997 |
Leptin receptor signaling in normal rats in vivo |
| Mary-Elizabeth Patti |
1996-1997 |
Role of amino acids in the induction of cellular insulin resistance |
| Evan Dale Abel |
1996-1998 |
Analysis of the impact of adipose tissue glucose transport on body weight, nutrient partitioning and glucose tolerance |
| Anthony Hollenberg |
1996-1998 |
Functional antagonism between C/EBP and PPAR on the leptin promoter |
| Wen Guo |
1997-1999 |
Effects of Exogenous Lipids on Fat Cell Metabolism |
| Jim Xiao |
1997-1999 |
Role of cyclin-dependent kinase inhibitors in differentiation of preadipocytes with aging |
| Rupert Yip |
1997-1999 |
The role of glucose-dependent insulinotropic polypeptide in fat metabolism |
| Zhijun Luo |
1998-2000 |
Role of MAPK family downstream of TNFa-receptor in insulin resistance |
| Christos Mantzoros |
1998-2000 |
Role of leptin in the neuroendocrine response to fasting |
| Megan McCrory |
1998-2000 |
Evaluation of the BOD POD air displacement plethysmograph for measuring body composition of obese and elderly subjects |
| Ron Morrison |
1998-2000 |
Molecular mechanisms contributing to the balance of adipocyte growth and differentiation |
| Edward Saltzman |
1998-2002 |
Feasibility of low and moderate intensity interventions to prevent weight gain in adults |
| Antonio Vidal-Puig |
1998-2000 |
Functional characterization of uncoupling proteins (UCPs) using adenoviral mediated gene transfer |
| S. Bryn Austin |
1999-2002 |
Assessment of environmental influences on diet, dieting, and physical activity in middle schools: A pilot instrument development project |
| Young-Bum Kim |
1999-2001 |
Signaling pathways mediating the effects of leptin on fat metabolism in muscle and adipose tissue |
| Tatyana Kupriyanova |
1999-2001 |
Isolation and identification of novel proteins in Glut4-vesicles |
| David Ludwig |
1999-2001 |
Dietary glycemic index and diabetes |
| Karen Miller |
1999-2001 |
Effects of dietary fat on leptin and menstrual function |
| Eric Rimm |
1999-2002 |
Effects of dietary and lifestyle characteristics on soluble tumor necrosis factor-receptors (sTNF-R) and IL-6 concentrations |
| Nicholas Tritos |
1999-2001 |
Characterization of the role of melanin concentrating hormone in glucose homeostasis employing a knockout and a transgenic model |
| Jude Deeney |
2001-2003 |
Lipid distribution in clonal pancreatic beta-cells studied with fluorescent fatty acids |
| Deborah Good |
2001-2003 |
Gene regulatory events mediating adult body weight control |
| Jianrong Han |
2002-2004 |
A new mechanism for adipocyte hyperplasia: fatty acids stimulates preadipocyte proliferation |
| Lora Heisler |
2001-2003 |
Central melanocortin and serotonergic systems: potential target pathways for obesity |
| Frank Hu |
2001-2003 |
Longitudinal analysis of dietary factors and childhood obesity in China |
| Jeffrey Lemmer |
2001-2002 |
Effect of sarcopenia on body composition and energy expenditure response to progressive resistance training |
| Christina Wee |
2001-2003 |
Quantifying how much patients value weight loss |
| Janice Zabolotny |
2001-2003 |
Role of protein tyrosine phosphatase 1B in leptin and insulin action in hypothalamus |
| Hui Hong Zhang |
2003-2005 |
The domains and mechanisms by which perilipin A modulate lipase actions on lipolysis |
| Nina Balthasar |
2003-2005 |
Assessing the physiological function of melanocortin-4-receptors (MC4R) in specific brain areas using a re-activatable MC4R null allele |
| Simin Liu |
2003-2005 |
Glycemic load, insulin sensitivity and plasma inflammatory markers in Type 2 diabetic patients: a randomized, controlled, crossover trial |
| Carine Lenders |
2003-2005 |
A multicenter randomized, placebo controlled, double blind trial of metformin in obese adolescents: characterization of amino acids |
| Iphigenia Tzameli |
2003-2005 |
Identification of endogenous PPARg ligands during an early phase of adipocyte differentiation |
| Kendra Bence |
2003-2005 |
Role of tyrosine phosphates in CNS control of energy balance |
| Harveen Dhillon |
2004-2006 |
VMH: A critical site in BW regulation of leptin |
| Adam Kennedy |
2004-2006 |
The molecular mechanism of ketogenic diet in the treatment of obesity |
| Lori Pbert |
2004-2006 |
Feasibility and structure of a systems-based intervention to prevent and treat obesity |
| Pavlos Pissios |
2004-2006 |
Generation of conditionally immortalized cell lines expressing melanin-concentrating hormone (MCH) |
| Diane Song |
2004-2006 |
Characterization of GIP signaling in adipocytes |
| Gordon Yaney |
2004-2006 |
Beta-cell hypersecretion seen in obesity: Alteration of the fatty acid incretin effect? |
| Jeffrey Zigman |
2004-2006 |
Selective expression of the ghrelin receptor (GHSR) within the arcuate nucleus |
| R. Wesley Farris II |
2005-2007 |
The Role of Insulin-Degrading Enzyme in Obesity and Metabolism |
| Erin Kershaw |
2005-2007 |
Regulation of Adipose Triglyceride Lipase (ATGL) by Insulin, TNF alpha, and PPAR gamma |
| Keith Tornheim |
2005-2007 |
Phosphofructokinase-M and adipose mass |
| Yu-Hua Tseng |
2005-2007 |
Role of BMPs on determination of brown vs. white adipocyte differentiation |
| Ouliana Ziouzenkova |
2005-2007 |
Studies on Retinaldehyde Functions in Adipogenesis |
| Caroline M. Apovian |
2006-2008 |
Use of MCT Oil for Enhancement of Weight Loss and Glycemic Control in Obese Diabetic Patients |
| Michael Badman |
2006-2009 |
Determination of the physiological role and Metabolic Effects of Fibroblast Growth Factor 21 |
| Katherine Strissel |
2006-2008 |
Do infiltrating macrophages have a role in adipose tissue remodeling in obesity? |
| Rob M. van Dam |
2006-2009 |
Effects of caffeinated and decaffeinated coffee on body weight and glucose tolerance |
| Alvaro Pascual-Leone |
2007-2009 |
Modulation of the dorsolateral prefontal cortex with repetitive transcranial magnetic stimulation in obesity |
| Bruce Bailey |
2007-2009 |
The influence of active gaming on energy expenditure and time spent in moderate to vigorous activity in overweight adolescents |
| Jamie Bodenlos |
2007-2008 |
Effect of acute VNS on consumption and preferences for sweets in depressed adults |
| Jody Dushay |
2007-2009 |
Potential regulation of FGF-21 by fasting and diet-induced ketosis in healthy adults |
| Efi Kokkotou |
2007-2009 |
Mechanisms of substance P effects on metabolism |
| Madhusmita Misra |
2007-2010 |
Neuroendocrine modulation of metabolic effects in overweight adolescent girls |
| Sherry Pagoto |
2007-2009 |
The role of stress in insulin resistance following bariatric surgery |
| Libin Liu |
2007-2009 |
The Role of Cavin/PTRF in Caveolae |
| Lu Qi |
2007-2009 |
Genome-Wide Association Based Scan for Abdominal Obesity Genes in Humans |
| Nicholas Stylopoulos |
2008-2009 |
Effects of Roux-En-Y Gastric Bypass on Diet Induced Thermogenesis in Mice |
| Qingchun Tong |
2007-2009 |
To Determine the Function of GABA Release from Agrp Neurons |
| Aaron Cypess |
2008-2009 |
Characterizing murine and human brown adipose tissue via PET/CT |
| Giulio Romeo |
2008-2009 |
Effects of profilin-1 in diet-induced obesity and adipose inflammation correlation with vascular outcomes |
| Jess Haines |
2008-2009 |
Maternal influences on adolescent weight and weight-related behaviors |
| Mark Herman |
2008-2009 |
The role of adipose tissue carbohydrate response element binding protein (ChREBP) in adipose tissue glucose metabolism and glucose homeostasis |
| Jongsoon Lee |
2008-2009 |
The role of circulating monocytes in the development of obesity-induced inflammation and insulin resistance |
| Yiqing Song |
2008-2009 |
Interrelationship of circulating levels of vitamin D, adiposity, and risk of developing type 2 diabetes in postmenopausal women |
| Qi Sun |
2008-2009 |
Obesity, physical activity, and successful aging |
| Thien Tran |
2008-2009 |
Identification of novel secretory proteins from subcutaneous fat that improve metabolism |
| Raphael Zoeller |
2008-2009 |
Use of a lipogenic mutant to investigate a novel link between carbohydrate and lipid metabolism |
| Hideo Makimura |
2010 |
The Effects of a Novel GH Releasing Factor on Mitochondrial Function |
| Vishwajeet Puri |
2010-2012 |
Role of FSP27 in fat metabolism and insulin sensitivity |
| Lisa Quintiliani |
2010-2012 |
A computer-based cue system for motivational interviewing counseling |
| Vetrivelan Ramalingam |
2010-2012 |
Sleep loss and circadian dysregulation – important risk factors for obesity and diabetes mellitus |
| Zhao Xu |
2010-2012 |
The role of promyelocytic leukemia zinc finger (PLZF) in adipogenesis |
| Sudha Biddinger |
2011-2012 |
Novel mechanisms by which insulin regulates the LDL receptor |
| Nicolas M. Oreskovic |
2011-2012 |
Use of GPS to Map Racial Variations in Adolescent Use of Space for Physical Activity |
| Linh Vong |
2011-2012 |
Leptin Action on GABAergic Neurons |
| Heather J. Baer |
2011-2012 |
Development of Tools within Electronic Health Records to Address Overweight and Obesity |
| Barbara Nikolajczyk |
2011-2012 |
The Role of T cells in the Transition to Type 2 Diabetes |
| Elaine W. Yu |
2011-2012 |
Effects of Bariatric Surgery on Bone Health |
| Katya Ravid |
2011-2012 |
The A2b adenosine receptor as regulator of type II diabetes |
| Fang Fang Zhang |
2011-2012 |
Obesity Among ALL Survivors: Preliminary Investigation of Diet and Energy Balance |
| Qin Yang |
2011-2012 |
Nicotinamide N-methyltransferase (NNMT) in obesity and insulin resistance |
