Irina V. Zhdanova, MD, Ph.D.
Dr. Zhdanova received her MD in Internal Medicine from the 1st Leningrad Medical Institute and has specialized in Clinical Physiology. She then received her PhD in Physiology of Behavior from the Institute of Experimental Medicine (St. Petersburg Russia). She completed her post-doctoral training at the Institute of Physiology (FIN), Russian Academy of Sciences, and then at the Massachusetts Institute of Technology (MIT).
Dr. Zhdanova is studying the role of circadian system in development and aging, and an impact of circadian factors on the effects of drugs of abuse. The studies in her laboratory employ non-human primates and zebrafish.
Dr. Zhdanova teaches in the Neuroscience course offered in the Medical School (AN703) and Cognitive Neuroscience graduate course.
Dr. Zhdanova is a member of the Department Qualifying Exam Committee (Chair) and the Medical School Executive Committee of the Cell and Molecular Biology program.
Sack RL; Auckley D; Auger RR; Carskadon MA; Wright KP; Vitiello MV; Zhdanova IV. Circadian rhythm sleep disorders: Part I, basic principles, shift work and jet lag disorders. SLEEP 2007; Nov 1;30(11):1460-83.
Sack R; Auckley D; Auger RR; Carskadon MA; Wright KP; Vitiello MV; Zhdanova IV. (2007) Circadian rhythm sleep disorders: Part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. SLEEP;Nov 1;30(11):1484-501.
Zhdanova IV, Yu L, Lopez-Patino M, Shang E, Kishi S, Guelin E (2008) Aging of the circadian system in zebrafish and the effects of melatonin on sleep and cognitive performance Brain Res Bull 75(2-4): 433-441.
Zhdanova, IV, Masuda K, Quasarano-Kourkoulis C, Rosene DL, Killiany RJ, Wang S. (2011) Aging of intrinsic circadian rhythms and sleep in a diurnal non-human primate, Macaca mulatta. Journal of Biological Rhythms J Biol Rhythms. 26(2):149-59.
Akle V., Guelin E., Yu, L., Brassard H., Slack BE, Zhdanova IV. (2012) F-spondin/spon1b expression patterns in developing and adult zebrafish. PLoS One 7(6):e37593
Hartsough EJ, Meyer RD, Chitalia V, Jiang Y, Marquez VE, Zhdanova IV, Weinberg J, Costello CE, Rahimi N. (2013) Lysine methylation promotes VEGFR-2 activation and angiogenesis. Science Signal. Dec 3;6(304):ra104.