Tara L. Moore, Ph.D.
Dr. Moore received her B.A. in psychology from the University of Calgary and her doctorate in Anatomy and Neurobiology from this department in 2000. She is currently a co-investigator in the Laboratory of Cognitive Neurobiology with Drs. Moss, Rosene, Killiany and Mortazavi. This laboratory investigates the effects of aging and age-related disease on the structure and function of the cerebral cortex in non-human primates.
Dr. Moore’s primary research interests involve the investigation of the recovery of fine motor function and re-organization of the motor cortex following an ischemic injury. Using a non-human primate (NHP) model of cortical ischemia developed with Dr. Rosene, she is establishing the rate and pattern of recovery of fine motor function of the hand and the histopathological response of the brain to ischemia in this model with young and aged NHPs. Additional studies with this model include assessing the efficacy of various therapeutics to enhance the recovery of function following ischemia.
Dr. Moore is also the Director of the graduate program MS in Forensic Anthropology. This program is designed to train individuals in the theory, practice, and methods of biological and skeletal anthropology employed by forensic anthropologists in medicolegal death investigations. Dr. Moore has completed training in human remains recovery with the Federal Bureau of Investigation and participated in the development of the Biomedical Forensic Sciences MS program.
Dr. Moore teaches Professional Skills and Human Anatomy and Osteology in the Forensic Anthropology program and Neurobiology of Aging in the department of Anatomy and Neurobiology. Dr. Moore is also a member of the Department of Neurology and is the Vice-Chair of the Institutional Animal Use and Care Committee and the Animal Research Advisory Committee at the School of Medicine.
Original, Peer Reviewed Articles
- Moore, TL, Pessina, MA, Finklestein, SP, Kramer, BC, Killiany, RJ, and Rosene, DL. (2013). Recovery of Fine Motor Performance After Ischemic Damage to Motor Cortex is Facilitated by Cell Therapy in the Rhesus Monkey. Somatosensory Motor Research. 2013 Jun 12. PMID: 23758412
- Moore TL, Schettler SP, Killiany RJ, Rosene DL, Moss MB. (2012) Impairment in delayed nonmatching to sample following lesions of dorsal prefrontal cortex. Behavioral Neuroscience. Dec; 126(6):772-80. doi: 10.1037/a0030493. Epub 2012 Oct 22. PMID: 23088539. PMCID: PMC3518867
- Moore, TL, Killiany, RJ, Pessina, MA, Moss, MB, Finklestein, SP, and Rosene, DL. (2012). Recovery from ischemia in the middle-aged brain: a non-human primate model. Neurobiology of Aging, Mar; 33(3):619.e9-619.e24. doi: 10.1016/j.neurobiolaging.2011.02.005. Epub 2011 Apr 1. PMID: 21458887. PMCID: PMC3145025
- Moore, TL, Killiany, RJ, Pessina, MA., Moss, MB and Rosene, DL. (2010) Assessment of Motor Function of the Hand in Aged Rhesus Monkeys. Somatosensory and Motor Research, 27 (3): 121-30. PMID:20653499
- Minett, WJ, Moore, TL., Juhascik, MM, Nields, HM., and Hull, MJ. (2010). Concentrations of Opiates and Psychotropic Agents in Polydrug Overdoses: A Surprising Correlation Between Morphine and Anti-Depressants. Journal of Forensic Science. Journal of Forensic Sciences 55 (5): 1319-1325. No PMCID located.
- Moore, TL, Schettler, SP, Killiany, RJ, Moss, MB, and Rosene, DL. (2009). Effects on Executive Function Following Damage to the Prefrontal Cortex in the Rhesus Monkey. Behavioral Neuroscience, 123 (2): 231-41. No PMCID located.
- Hynynen K, McDannold N, Clement G, Jolesz FA, Zadicario E, Killiany R, Moore T, Rosene D. (2006) Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain–a primate study. Eur J Radiol. 59(2):149-56.
- Makris N, Papadimitriou GM, van der Kouwe A, Kennedy DN, Hodge SM, Dale AM, Benner T, Wald LL, Wu O, Tuch DS, Caviness VS, Moore TL, Killiany RJ, Moss MB, Rosene DL. (2006). Frontal connections and cognitive changes in normal aging rhesus monkeys: A DTI study. Neurobiology of Aging;28 (10):1556-67.
- Moore, T.L., Killiany, R.J., Herndon, J.G., Rosene, D.L. and Moss, MB. (2006). Executive system dysfunction occurs as early as middle-age in the rhesus monkey. Neurobiology of Aging;27(10):1484-93.
- Moore, T.L., Killiany, R.J., Herndon, J.G., Rosene, D.L. and Moss, MB. (2005). A non-human primate test of abstraction and set shifting: an automated adaptation of the Wisconsin card sorting test. Journal of Neuroscience Methods, 146 (2): 165-73.
- Moore, T.L., Schettler, S.P., Herndon, H.G., Killiany, R.J., Moss, M.B. and Rosene, D.L. (2005). Cognitive impairment in aged rhesus monkeys Associated with monoamine receptors in the prefrontal cortex. Behavioral Brain Research, 160 (2); 208-221.
- Lacreuse A, Kim CB, Rosene DL, Killiany RJ, Moore TL, Moss MB, Chennareddi L, Herndon JG. (2005). Sex, age and training modulate spatial memory in the rhesus monkey. Behavioral Neuroscience, 119:118-126.
- Luebke, J.I., Chang, Y., Moore, T.L. and Rosene, D.L. (2004). Normal Aging Results in Decreased Synaptic Excitation and Increased Synaptic Inhibition of Layer 2/3 Pyramidal Cells in the Monkey Prefrontal Cortex. Neuroscience, 125; 277-288.
- Moore, T.L., Killiany, R.J., Herndon, J,G., Rosene, D.L., and Moss, M.B. (2003) Impairment in Abstraction and Set Shifting in Aged Rhesus Monkey. Neurobiology of Aging. 24 (1); 125-134.
- Moore, T.L., Killiany, R.J., Rosene, D.L., Prusty, S., Hollander, W., and Moss, M.B. (2003). Hypertension Induced Changes in Monoamine Receptors in the Prefrontal Cortex of Rhesus Monkeys. Neuroscience, 120 (1); 177-189.
- Moore, T.L., Killiany, R.J., Rosene, D.L., Prusty, S., Hollander, W., and Moss, M.B. (2002). Impairment of Executive Function Induced by Hypertension in the Rhesus Monkey. Behavioral Neuroscience, 116 (3); 387-396.
- Moss, MB, Moore, TL, Schettler, SP, Killiany, RJ, and Rosene, DL. (2007). Successful vs. Unsuccessful Aging in the Rhesus Monkey. In: Brain Aging (Riddle, DR, ed). CRC Press New York.
- Killiany, R.J., Moore, T.L, and Rehbein, L. and Moss, MB. (2005). Memory and Executive Function and Autism. In: Neurobiology of Autism, 2nd Ed. (Kemper, TL and Bauman, M., eds). John Hopkins University Press, Baltimore.