Gene J. Blatt, Ph.D.

blatt

Associate Professor

Phone: 617-638-5260
Fax: 617-638-4216
Email: gblatt@bu.edu
Location: R – 1003, BUSM

Dr. Blatt received his doctorate in Anatomy with a concentration in Neuroscience from Thomas Jefferson University in 1986 studying the olivocerebellar system in spontaneous varieties of genetic mutations in mice. He completed postdoctoral training in Neuroanatomy and Neurophysiology at the Salk Institute in LaJolla, California 1985-87 studying response properties and connectivity of posterior parietal cortical neurons in primates.

Dr. Blatt became a Research Associate in the Department of Anatomy and Neurobiology at BUSM in 1987, studying primate limbic system connectivity. In 1991, he became a Research Assistant Professor; in 1994 Assistant Professor and is currently an Associate Professor. Dr. Blatt’s current research focuses on the neuropathology of autism studying cerebellar, limbic, and speech and language systems. Recently, he has been pursuing the involvement of the GABAergic, serotonergic and glutamatergic systems in autism and the developmental timing of the disorder.

Dr. Blatt is also the editor and chapter author in a book entitled The Neurochemical Basis of Autism; Molecules to Mini-Columns (Springer Publishers, NY. Release date December 2009).

Dr. Blatt has taught in all three major departmental courses offered to medical and graduate students: Neurosciences, Histology and Gross Anatomy, in which he served as Course Manager from 1994-2000. He organized a graduate course with Dr. Kemper in the Neuroanatomical Basis of Neurological Disorders which has been well received by departmental graduate students.

Dr. Blatt’s current service commitments include the Faculty Development and Promotions committee, the Department Qualifying Examination Committee, and is the Chair of the BUSM Academic Policy Committee. He is an advisor to the Graduate Division Masters in Medical Science students and an advisor-at-large in the BUSM Crumpler Academy. He also interviews MD/PhD students for BUSM. Dr. Blatt additionally serves on the Editorial Board of the flagship Autism journal Autism Research, and as a grant reviewer for NIH.

Recent Publications

Lawrence YA, Kemper TL, Bauman ML, Blatt GJ. (2009) Parvalbumin-, calbindin-, and calretinin-immunoreactive hippocampal interneuron density in autism. Acta Neurol Scand. [Epub ahead of print].

Oblak A, Gibbs TT, Blatt GJ. (2009) Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism. Autism Res. 2(4):205-19.

Simms ML, Kemper TL, Timbie CM, Bauman ML, Blatt GJ. (2009) The anterior cingulate cortex in autism: heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups. Acta Neuropathol. [Epub ahead of print]

Yip J, Soghomonian JJ, Blatt GJ. (2009) Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study. Autism Res. 2(1):50-9.

Whitney ER, Kemper TL, Rosene DL, Bauman ML, Blatt GJ. (2009) Density of cerebellar basket and stellate cells in autism: evidence for a late developmental loss of Purkinje cells. J Neurosci Res. 87(10):2245-54.

Whitney ER, Kemper TL, Bauman ML, Rosene DL, Blatt GJ. (2008) Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k. Cerebellum. 7(3):406-16.

Yip J, Soghomonian JJ, Blatt GJ. (2008) Increased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunction. J Neurosci Res. 86(3):525-30.

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October 2, 2009
Primary teaching affiliate
of BU School of Medicine